Psg20 pregnancy-specific beta-1-glycoprotein 20 [Mus musculus (house mouse)] - Gene

Summary

Official Symbol: Psg20provided by MGI
Official Full Name: pregnancy-specific beta-1-glycoprotein 20provided by MGI
Primary source: MGI:MGI:1891352
See related: Ensembl:ENSMUSG00000063305 AllianceGenome:MGI:1891352
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Mus musculus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
Also known as: Cea7; EG434540
Summary: Predicted to enable protein heterodimerization activity. Predicted to be involved in T cell activation and immune response. Predicted to be located in several cellular components, including apical plasma membrane; cell surface; and extracellular space. Predicted to be active in external side of plasma membrane. Orthologous to several human genes including CEACAM4 (CEA cell adhesion molecule 4); CEACAM7 (CEA cell adhesion molecule 7); and CEACAM8 (CEA cell adhesion molecule 8). [provided by Alliance of Genome Resources, Nov 2024]
Expression: Biased expression in placenta adult (RPKM 1.5) and testis adult (RPKM 0.1) See more
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Location:: 7 A3; 7 9.23 cM

Exon count:: 6

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCm39 (GCF_000001635.27)	7	NC_000073.7 (18407910..18420218, complement)
108.20200622	previous assembly	GRCm38.p6 (GCF_000001635.26)	7	NC_000073.6 (18673985..18686277, complement)

Chromosome 7 - NC_000073.7 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Expression

Go to the top of the page Help

See details

Project title: Mouse ENCODE transcriptome data Mouse ENCODE transcriptome data
Description: RNA profiling data sets generated by the Mouse ENCODE project.
BioProject: PRJNA66167
Publication: PMID 25409824
Analysis date: n/a

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

Variation

Go to the top of the page Help

Alleles

Alleles of this type are documented at Mouse Genome Informatics (MGI)

Endonuclease-mediated (1)

General gene information

Go to the top of the page Help

Gene Ontology Provided by MGI

Function	Evidence Code	Pubs
enables molecular_function	ND No biological Data available more info
enables protein heterodimerization activity	ISO Inferred from Sequence Orthology more info

Process	Evidence Code	Pubs
involved_in T cell activation	IBA Inferred from Biological aspect of Ancestor more info
involved_in immune response	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
located_in apical plasma membrane	ISO Inferred from Sequence Orthology more info
located_in cell surface	ISO Inferred from Sequence Orthology more info
is_active_in cellular_component	ND No biological Data available more info
located_in cytosol	ISO Inferred from Sequence Orthology more info
is_active_in external side of plasma membrane	IBA Inferred from Biological aspect of Ancestor more info
located_in extracellular space	ISO Inferred from Sequence Orthology more info
located_in plasma membrane	ISO Inferred from Sequence Orthology more info

General protein information

Go to the top of the page Help

Preferred Names: pregnancy-specific glycoprotein 20

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_054058.1 → NP_473399.1 pregnancy-specific glycoprotein 20 precursor

Status: VALIDATED

Source sequence(s)

AC165084

Conserved Domains (3) summary

cd05774
Location:156 → 260

Ig_CEACAM_D1; First immunoglobulin (Ig)-like domain of carcinoembryonic antigen (CEA) related cell adhesion molecule (CEACAM)

smart00408
Location:400 → 461

IGc2; Immunoglobulin C-2 Type

smart00410
Location:395 → 472

IG_like; Immunoglobulin like

RefSeqs of Annotated Genomes: GCF_000001635.27-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCm39 C57BL/6J

Genomic

NC_000073.7 Reference GRCm39 C57BL/6J

Range

18407910..18420218 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_030242757.2 → XP_030098617.1 pregnancy-specific glycoprotein 20 isoform X1

UniProtKB/TrEMBL

E9Q6J6

Related

ENSMUSP00000104122.2, ENSMUST00000108482.8

Conserved Domains (2) summary

smart00408
Location:397 → 458

IGc2; Immunoglobulin C-2 Type

cd05774
Location:156 → 260

Ig_CEACAM_D1; First immunoglobulin (Ig)-like domain of carcinoembryonic antigen (CEA) related cell adhesion molecule (CEACAM)