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CG10000 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 43394, updated on 2-Nov-2024

Summary

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Official Symbol
CG10000provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0039596
Locus tag
Dmel_CG10000
See related
AllianceGenome:FB:FBgn0039596
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG10000; dppGalNAcT10
Summary
Predicted to enable polypeptide N-acetylgalactosaminyltransferase activity. Involved in sexual reproduction. Predicted to be active in Golgi apparatus. Is expressed in embryonic/larval midgut. Orthologous to human GALNT14 (polypeptide N-acetylgalactosaminyltransferase 14) and GALNT16 (polypeptide N-acetylgalactosaminyltransferase 16). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
all
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Genomic context

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See CG10000 in Genome Data Viewer
Location:
98E3-98E3; 3-97 cM
Exon count:
7
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (28748384..28751661, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (24574106..24577383, complement)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene huntingtin Neighboring gene Allatostatin A receptor 2 Neighboring gene uncharacterized protein Neighboring gene aquarius

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional characterization and expression analysis of members of the UDP-GalNAc:polypeptide N-acetylgalactosaminyltransferase family from Drosophila melanogaster. Ten Hagen KG, et al. J Biol Chem, 2003 Sep 12. PMID 12829714
  2. Expression of the UDP-GalNAc: polypeptide N-acetylgalactosaminyltransferase family is spatially and temporally regulated during Drosophila development. Tian E, et al. Glycobiology, 2006 Feb. PMID 16251381
  3. Multiple members of the UDP-GalNAc: polypeptide N-acetylgalactosaminyltransferase family are essential for viability in Drosophila. Tran DT, et al. J Biol Chem, 2012 Feb 17. PMID 22157008, Free PMC Article
  4. Dissecting the biological role of mucin-type O-glycosylation using RNA interference in Drosophila cell culture. Zhang L, et al. J Biol Chem, 2010 Nov 5. PMID 20807760, Free PMC Article
  5. An O-glycosyltransferase promotes cell adhesion during development by influencing secretion of an extracellular matrix integrin ligand. Zhang L, et al. J Biol Chem, 2010 Jun 18. PMID 20371600, Free PMC Article

See all (30) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables polypeptide N-acetylgalactosaminyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables polypeptide N-acetylgalactosaminyltransferase activity ISS
Inferred from Sequence or Structural Similarity
more info
  
Process Evidence Code Pubs
involved_in oligosaccharide biosynthetic process ISS
Inferred from Sequence or Structural Similarity
more info
  
involved_in protein O-linked glycosylation IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in sexual reproduction IEP
Inferred from Expression Pattern
more info
 PubMed 
Component Evidence Code Pubs
is_active_in Golgi apparatus IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG10000-PA
NP_651630.3

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    28748384..28751661 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_143373.3 → NP_651630.3  uncharacterized protein Dmel_CG10000 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_651630.3

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q8MYY6, Q9VAT9
    UniProtKB/TrEMBL
    H8F4S3
    Related
    FBpp0084684
    Conserved Domains (2) summary
    cd02510
    Location:113 → 422
    pp-GalNAc-T; pp-GalNAc-T initiates the formation of mucin-type O-linked glycans
    pfam00652
    Location:435 → 548
    Ricin_B_lectin; Ricin-type beta-trefoil lectin domain
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8MYY6.2 Q8MYY6

Gene LinkOut

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