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grass Gram-positive Specific Serine protease [ Drosophila melanogaster (fruit fly) ]

Gene ID: 43273, updated on 28-Oct-2024

Summary

Official Symbol
grassprovided by FlyBase
Official Full Name
Gram-positive Specific Serine proteaseprovided by FlyBase
Primary source
FLYBASE:FBgn0039494
Locus tag
Dmel_CG5896
See related
AllianceGenome:FB:FBgn0039494
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
c-SP1; CG5896; cSP1; Dmel\CG5896; Grass; SP1; SP2
Summary
Enables calcium ion binding activity. Involved in Toll receptor ligand protein activation cascade; defense response to other organism; and positive regulation of antimicrobial peptide production. Located in extracellular region. Is expressed in embryonic salivary gland duct and embryonic/larval tracheal dorsal trunk. [provided by Alliance of Genome Resources, Oct 2024]
Orthologs
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Genomic context

See grass in Genome Data Viewer
Location:
97E5-97E5; 3-92 cM
Exon count:
6
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (27157948..27159781)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (22983670..22985503)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene Malic enzyme b Neighboring gene uncharacterized protein Neighboring gene pickpocket 31 Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by FlyBase

Component Evidence Code Pubs
located_in extracellular region HDA PubMed 
located_in extracellular region IC
Inferred by Curator
more info
PubMed 
is_active_in extracellular space IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
Gram-positive specific serine protease
Names
CG5896-PA
CG5896-PB
Gram-positive-specific serine protease
gram-positive specific serine protease
grass
grass-PA
grass-PB
herrade
NP_651543.1
NP_733197.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    27157948..27159781
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_170318.3NP_733197.1  Gram-positive specific serine protease, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_733197.1

    Status: REVIEWED

    Related
    FBpp0084481
    Conserved Domains (3) summary
    smart00680
    Location:148
    CLIP; Clip or disulphide knot domain
    smart00020
    Location:76326
    Tryp_SPc; Trypsin-like serine protease
    cd00190
    Location:79329
    Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
  2. NM_143286.3NP_651543.1  Gram-positive specific serine protease, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_651543.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q86PB3, Q8MR95, Q9VB67, Q9VB68
    Related
    FBpp0084482
    Conserved Domains (2) summary
    smart00680
    Location:3290
    CLIP; Clip or disulphide knot domain
    cd00190
    Location:121371
    Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...