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slc44a1.L solute carrier family 44 (choline transporter), member 1 L homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 432345, updated on 4-Nov-2024

Summary

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Official Symbol
slc44a1.L
Official Full Name
solute carrier family 44 (choline transporter), member 1 L homeolog
Primary source
Xenbase:XB-GENE-984340
Locus tag
XELAEV_18006741mg
See related
EnsemblRapid:ENSXLAG00005036381 AllianceGenome:Xenbase:XB-GENE-984340
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
ctl1; slc44a1
Summary
Predicted to enable choline transmembrane transporter activity and ethanolamine transmembrane transporter activity. Predicted to act upstream of or within choline transport and ethanolamine transport. Predicted to be located in mitochondrial outer membrane and plasma membrane. Human ortholog(s) of this gene implicated in high grade glioma. Orthologous to human SLC44A1 (solute carrier family 44 member 1). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See slc44a1.L in Genome Data Viewer
Location:
chromosome: 1L
Exon count:
19
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 1L NC_054371.1 (129993394..130076481)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 1L NC_030724.1 (117701139..117784388)

Chromosome 1L - NC_054371.1Genomic Context describing neighboring genes Neighboring gene nipsnap homolog 3A L homeolog Neighboring gene ATP binding cassette subfamily A member 1 L homeolog Neighboring gene uncharacterized LOC108713854 Neighboring gene fibronectin type III and SPRY domain containing 1-like L homeolog Neighboring gene fukutin-like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Clone Names

  • MGC80706, MGC82240

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables antiporter activity IEA
Inferred from Electronic Annotation
more info
  
enables choline transmembrane transporter activity ISS
Inferred from Sequence or Structural Similarity
more info
  
enables ethanolamine transmembrane transporter activity ISS
Inferred from Sequence or Structural Similarity
more info
  
enables transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within choline transport ISS
Inferred from Sequence or Structural Similarity
more info
  
acts_upstream_of_or_within ethanolamine transport ISS
Inferred from Sequence or Structural Similarity
more info
  
acts_upstream_of_or_within transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in mitochondrial outer membrane IEA
Inferred from Electronic Annotation
more info
  
located_in mitochondrial outer membrane ISS
Inferred from Sequence or Structural Similarity
more info
  
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
  
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  
located_in plasma membrane ISS
Inferred from Sequence or Structural Similarity
more info
  

General protein information

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Preferred Names
choline transporter-like protein 1
Names
solute carrier family 44, member 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001091778.1 → NP_001085247.1  choline transporter-like protein 1

    See identical proteins and their annotated locations for NP_001085247.1

    Status: PROVISIONAL

    Source sequence(s)
    BC082837
    UniProtKB/Swiss-Prot
    Q63ZS3, Q6IR74
    UniProtKB/TrEMBL
    A0A1L8HXU2, A0A974E114
    Related
    ENSXLAP00005108892.1, ENSXLAT00005111055.1
    Conserved Domains (1) summary
    pfam04515
    Location:290 → 600
    Choline_transpo; Plasma-membrane choline transporter

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054371.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    129993394..130076481
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_041579895.1 → XP_041435829.1  choline transporter-like protein 1 isoform X1

    UniProtKB/Swiss-Prot
    Q63ZS3, Q6IR74
    UniProtKB/TrEMBL
    A0A1L8HXU2, A0A974E114
    Related
    ENSXLAP00005108873.1, ENSXLAT00005111037.1
    Conserved Domains (1) summary
    pfam04515
    Location:290 → 600
    Choline_transpo; Plasma-membrane choline transporter
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q6IR74.2 GenPept UniProtKB/Swiss-Prot:Q6IR74

Gene LinkOut

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