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polr3e.L polymerase (RNA) III (DNA directed) polypeptide E (80kD) L homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 432325, updated on 4-Nov-2024

Summary

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Official Symbol
polr3e.L
Official Full Name
polymerase (RNA) III (DNA directed) polypeptide E (80kD) L homeolog
Primary source
Xenbase:XB-GENE-998801
Locus tag
XELAEV_18045335mg
See related
EnsemblRapid:ENSXLAG00005014443 AllianceGenome:Xenbase:XB-GENE-998801
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
polr3e
Summary
Acts upstream of or within face development; forebrain development; and midbrain development. Predicted to be located in nucleus. Predicted to be part of RNA polymerase III complex. Orthologous to human POLR3E (RNA polymerase III subunit E). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See polr3e.L in Genome Data Viewer
Location:
chromosome: 9_10L
Exon count:
22
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 9_10L NC_054387.1 (111399720..111436900, complement)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 9_10L NC_030740.1 (100798712..100835935, complement)

Chromosome 9_10L - NC_054387.1Genomic Context describing neighboring genes Neighboring gene transmembrane protein 180 Neighboring gene cerebellar degeneration related protein 2 L homeolog Neighboring gene eukaryotic elongation factor 2 kinase L homeolog Neighboring gene transfer RNA leucine (anticodon UAG)

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Functional assessment of the "two-hit" model for neurodevelopmental defects in Drosophila and X. laevis. Pizzo L, et al. PLoS Genet, 2021 Apr. PMID 33819264, Free PMC Article
  2. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Clone Names

  • MGC78924

Gene Ontology Provided by Xenbase

Process Evidence Code Pubs
acts_upstream_of_or_within DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within face development IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within forebrain development IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within midbrain development IMP
Inferred from Mutant Phenotype
more info
 PubMed 
acts_upstream_of_or_within tRNA transcription by RNA polymerase III IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
part_of RNA polymerase III complex IEA
Inferred from Electronic Annotation
more info
  
located_in nucleus IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
polymerase (RNA) III (DNA directed) polypeptide E (80kD) L homeolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001091761.1 → NP_001085230.1  polymerase (RNA) III (DNA directed) polypeptide E (80kD) L homeolog

    See identical proteins and their annotated locations for NP_001085230.1

    Status: PROVISIONAL

    Source sequence(s)
    BC072054
    UniProtKB/TrEMBL
    A0A974H466, Q6IP64
    Related
    ENSXLAP00005042272.1, ENSXLAT00005043339.1
    Conserved Domains (1) summary
    pfam04801
    Location:5 → 432
    Sin_N; Sin-like protein conserved region

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054387.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    111399720..111436900 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_041575590.1 → XP_041431524.1  polymerase (RNA) III (DNA directed) polypeptide E (80kD) L homeolog isoform X1

    UniProtKB/TrEMBL
    A0A974H466, Q6IP64
    Related
    ENSXLAP00005042279.1, ENSXLAT00005043344.1
    Conserved Domains (1) summary
    pfam04801
    Location:5 → 432
    Sin_N; Sin-like protein conserved region
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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