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lims1.L LIM-type zinc finger domains 1 L homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 432196, updated on 4-Nov-2024

Summary

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Official Symbol
lims1.L
Official Full Name
LIM-type zinc finger domains 1 L homeolog
Primary source
Xenbase:XB-GENE-6255974
Locus tag
XELAEV_18012919mg
See related
EnsemblRapid:ENSXLAG00005011262 AllianceGenome:Xenbase:XB-GENE-6255974
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
lims1; pinch; lims1b; pinch1; Pinch-1; lims1-a; lims1-b; lims1.S
Summary
Predicted to enable metal ion binding activity. Predicted to act upstream of or within several processes, including cell-cell junction organization; positive regulation of integrin-mediated signaling pathway; and positive regulation of substrate adhesion-dependent cell spreading. Predicted to be located in cell-cell junction; cytoplasm; and focal adhesion. Orthologous to human LIMS1 (LIM zinc finger domain containing 1). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See lims1.L in Genome Data Viewer
Location:
chromosome: 2L
Exon count:
13
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 2L NC_054373.1 (113617670..113694948, complement)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 2L NC_030726.1 (107786148..107863748, complement)

Chromosome 2L - NC_054373.1Genomic Context describing neighboring genes Neighboring gene coiled-coil domain containing 138 L homeolog Neighboring gene RAN binding protein 2 L homeolog Neighboring gene solute carrier family 5 (sodium/choline cotransporter), member 7 L homeolog Neighboring gene ST6 beta-galactosamide alpha-2,6-sialyltranferase 2 L homeolog Neighboring gene multiple tissue opsin 2 L homeolog

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Clone Names

  • MGC81174

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within cell-cell adhesion IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within cell-cell junction organization IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within positive regulation of integrin-mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within positive regulation of substrate adhesion-dependent cell spreading IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in cell-cell junction IEA
Inferred from Electronic Annotation
more info
  
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in focal adhesion IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
LIM-type zinc finger domains 1 L homeolog
Names
LIM and senescent cell antigen-like domains 1 b
LIM-type zinc finger domains 1 S homeolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001091652.1 → NP_001085121.1  LIM-type zinc finger domains 1 L homeolog

    See identical proteins and their annotated locations for NP_001085121.1

    Status: PROVISIONAL

    Source sequence(s)
    BC072204
    UniProtKB/TrEMBL
    A7LBJ1, Q6INR9
    Related
    ENSXLAP00005033065.1, ENSXLAT00005033858.1
    Conserved Domains (5) summary
    cd09331
    Location:21 → 79
    LIM1_PINCH; The first LIM domain of protein PINCH
    cd09332
    Location:82 → 133
    LIM2_PINCH; The second LIM domain of protein PINCH
    cd09333
    Location:146 → 196
    LIM3_PINCH; The third LIM domain of protein PINCH
    cd09334
    Location:202 → 255
    LIM4_PINCH; The fourth LIM domain of protein PINCH
    cd09335
    Location:263 → 316
    LIM5_PINCH; The fifth LIM domain of protein PINCH

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054373.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    113617670..113694948 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_041580954.1 → XP_041436888.1  LIM-type zinc finger domains 1 L homeolog isoform X1

    UniProtKB/TrEMBL
    A0A8J1M5C2, A7LBJ1
    Conserved Domains (5) summary
    cd09331
    Location:21 → 79
    LIM1_PINCH; The first LIM domain of protein PINCH
    cd09332
    Location:82 → 133
    LIM2_PINCH; The second LIM domain of protein PINCH
    cd09333
    Location:146 → 196
    LIM3_PINCH; The third LIM domain of protein PINCH
    cd09334
    Location:202 → 255
    LIM4_PINCH; The fourth LIM domain of protein PINCH
    cd09335
    Location:263 → 316
    LIM5_PINCH; The fifth LIM domain of protein PINCH

  2. XM_041580957.1 → XP_041436891.1  LIM-type zinc finger domains 1 L homeolog isoform X4

    UniProtKB/TrEMBL
    A0A8J1M6F7, A7LBJ1
    Conserved Domains (5) summary
    cd09331
    Location:47 → 105
    LIM1_PINCH; The first LIM domain of protein PINCH
    cd09332
    Location:108 → 159
    LIM2_PINCH; The second LIM domain of protein PINCH
    cd09333
    Location:172 → 222
    LIM3_PINCH; The third LIM domain of protein PINCH
    cd09334
    Location:228 → 281
    LIM4_PINCH; The fourth LIM domain of protein PINCH
    cd09335
    Location:289 → 342
    LIM5_PINCH; The fifth LIM domain of protein PINCH

  3. XM_041580958.1 → XP_041436892.1  LIM-type zinc finger domains 1 L homeolog isoform X5

    UniProtKB/TrEMBL
    A0A8J1M5C6, A7LBJ1
    Related
    ENSXLAP00005033076.1, ENSXLAT00005033870.1
    Conserved Domains (5) summary
    cd09331
    Location:47 → 105
    LIM1_PINCH; The first LIM domain of protein PINCH
    cd09332
    Location:108 → 159
    LIM2_PINCH; The second LIM domain of protein PINCH
    cd09333
    Location:172 → 222
    LIM3_PINCH; The third LIM domain of protein PINCH
    cd09334
    Location:228 → 281
    LIM4_PINCH; The fourth LIM domain of protein PINCH
    cd09335
    Location:289 → 342
    LIM5_PINCH; The fifth LIM domain of protein PINCH

  4. XM_041580955.1 → XP_041436889.1  LIM-type zinc finger domains 1 L homeolog isoform X2

    UniProtKB/TrEMBL
    A0A8J1M5C8, A0A974DI34
    Related
    ENSXLAP00005033081.1, ENSXLAT00005033875.1
    Conserved Domains (5) summary
    cd09331
    Location:73 → 131
    LIM1_PINCH; The first LIM domain of protein PINCH
    cd09332
    Location:134 → 185
    LIM2_PINCH; The second LIM domain of protein PINCH
    cd09333
    Location:198 → 248
    LIM3_PINCH; The third LIM domain of protein PINCH
    cd09334
    Location:254 → 307
    LIM4_PINCH; The fourth LIM domain of protein PINCH
    cd09335
    Location:315 → 368
    LIM5_PINCH; The fifth LIM domain of protein PINCH

  5. XM_041580956.1 → XP_041436890.1  LIM-type zinc finger domains 1 L homeolog isoform X3

    UniProtKB/TrEMBL
    A0A8J1M769, A0A974DI34
    Related
    ENSXLAP00005033072.1, ENSXLAT00005033866.1
    Conserved Domains (5) summary
    cd09331
    Location:73 → 131
    LIM1_PINCH; The first LIM domain of protein PINCH
    cd09332
    Location:134 → 185
    LIM2_PINCH; The second LIM domain of protein PINCH
    cd09333
    Location:198 → 248
    LIM3_PINCH; The third LIM domain of protein PINCH
    cd09334
    Location:254 → 307
    LIM4_PINCH; The fourth LIM domain of protein PINCH
    cd09335
    Location:315 → 368
    LIM5_PINCH; The fifth LIM domain of protein PINCH
Nucleotide Protein Strain
Heading Accession and Version

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