slc17a7.S solute carrier family 17 (vesicular glutamate transporter), member 7 S homeolog [Xenopus laevis (African clawed frog)] - Gene

Summary

Official Symbol: slc17a7.S
Official Full Name: solute carrier family 17 (vesicular glutamate transporter), member 7 S homeolog
Primary source: Xenbase:XB-GENE-6493995
Locus tag: XELAEV_18037823mg
See related: EnsemblRapid:ENSXLAG00005011538 AllianceGenome:Xenbase:XB-GENE-6493995
Gene type: protein coding
RefSeq status: MODEL
Organism: Xenopus laevis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as: bnpi; Xvglut; vglut2; Xvglut1; slc17a6; slc17a7; slc17a8; slc17a8.L
Summary: Predicted to enable chloride channel activity and secondary active transmembrane transporter activity. Predicted to act upstream of or within several processes, including L-glutamate transmembrane transport; chloride transport; and sodium-dependent phosphate transport. Predicted to be located in synaptic vesicle membrane. Predicted to be part of chloride channel complex. Orthologous to human SLC17A7 (solute carrier family 17 member 7). [provided by Alliance of Genome Resources, Nov 2024]
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Location:: chromosome: 7S

Exon count:: 12

Annotation release	Status	Assembly	Chr	Location
101	current	Xenopus_laevis_v10.1 (GCF_017654675.1)	7S	NC_054384.1 (98659335..98713718, complement)
100	previous assembly	Xenopus_laevis_v2 (GCF_001663975.1)	7S	NC_030737.1 (79518617..79573873, complement)

Chromosome 7S - NC_054384.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

Go to the top of the page Help

Homology

Orthologs from OrthoDB

Clone Names

MGC83509

Gene Ontology Provided by Xenbase

Function	Evidence Code	Pubs
enables L-glutamate transmembrane transporter activity	IEA Inferred from Electronic Annotation more info
enables L-glutamate uniporter activity	ISS Inferred from Sequence or Structural Similarity more info
enables antiporter activity	IEA Inferred from Electronic Annotation more info
enables chloride channel activity	IEA Inferred from Electronic Annotation more info
enables chloride channel activity	ISS Inferred from Sequence or Structural Similarity more info
enables neurotransmitter transmembrane transporter activity	IEA Inferred from Electronic Annotation more info
enables phosphate ion uniporter activity	ISS Inferred from Sequence or Structural Similarity more info
enables potassium:proton antiporter activity	ISS Inferred from Sequence or Structural Similarity more info
enables sodium:phosphate symporter activity	ISS Inferred from Sequence or Structural Similarity more info
enables symporter activity	IEA Inferred from Electronic Annotation more info
enables transmembrane transporter activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within L-glutamate transmembrane transport	ISS Inferred from Sequence or Structural Similarity more info
acts_upstream_of_or_within chloride transport	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within chloride transport	ISS Inferred from Sequence or Structural Similarity more info
acts_upstream_of_or_within monoatomic anion transport	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within monoatomic ion transmembrane transport	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within neurotransmitter loading into synaptic vesicle	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within neurotransmitter transport	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within phosphate ion transport	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within phosphate ion transport	ISS Inferred from Sequence or Structural Similarity more info
acts_upstream_of_or_within potassium ion transport	ISS Inferred from Sequence or Structural Similarity more info
acts_upstream_of_or_within regulation of synapse structure or activity	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within sodium ion transport	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within sodium-dependent phosphate transport	ISS Inferred from Sequence or Structural Similarity more info
acts_upstream_of_or_within synaptic transmission, glutamatergic	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within transmembrane transport	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
part_of chloride channel complex	IEA Inferred from Electronic Annotation more info
located_in cytoplasmic vesicle	IEA Inferred from Electronic Annotation more info
located_in excitatory synapse	IEA Inferred from Electronic Annotation more info
located_in neuron projection	IEA Inferred from Electronic Annotation more info
located_in plasma membrane	IEA Inferred from Electronic Annotation more info
located_in synapse	IEA Inferred from Electronic Annotation more info
located_in synaptic vesicle membrane	IEA Inferred from Electronic Annotation more info
located_in synaptic vesicle membrane	ISS Inferred from Sequence or Structural Similarity more info

General protein information

Go to the top of the page Help

Preferred Names: vesicular glutamate transporter 1

Names: VGluT1; solute carrier family 17 (sodium-dependent inorganic phosphate cotransporter), member 8; solute carrier family 17 (vesicular glutamate transporter), member 8 L homeolog; solute carrier family 17 member 6; solute carrier family 17 member 7; vesicular glutamate transporter 2

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

NC_054384.1 Reference Xenopus_laevis_v10.1 Primary Assembly

Range

98659335..98713718 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_041571609.1 → XP_041427543.1 vesicular glutamate transporter 1

UniProtKB/Swiss-Prot

Q6INC8

UniProtKB/TrEMBL

A0A1L8FH30, A0A974CCY6, A0A974CHA7

Related

ENSXLAP00005033775.1, ENSXLAT00005034614.1

Conserved Domains (1) summary

cd17382
Location:66 → 490

MFS_SLC17A6_7_8_VGluT; Solute carrier family 17 members 6, 7, and 8 (also called Vesicular glutamate transporters) of the Major Facilitator Superfamily of transporters

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

NM_001091612.1: Suppressed sequence

Description

NM_001091612.1: This RefSeq was removed because it is a nonsense-mediated mRNA decay (NMD) candidate.