ephx1.L epoxide hydrolase 1, microsomal (xenobiotic) L homeolog [Xenopus laevis (African clawed frog)] - Gene

Summary

Official Symbol: ephx1.L
Official Full Name: epoxide hydrolase 1, microsomal (xenobiotic) L homeolog
Primary source: Xenbase:XB-GENE-995309
Locus tag: XELAEV_18026283mg
See related: EnsemblRapid:ENSXLAG00005032375 AllianceGenome:Xenbase:XB-GENE-995309
Gene type: protein coding
RefSeq status: MODEL
Organism: Xenopus laevis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as: meh; ephx; epox; ephx1
Summary: Predicted to enable cis-stilbene-oxide hydrolase activity. Predicted to act upstream of or within catabolic process and epoxide metabolic process. Predicted to be located in endoplasmic reticulum membrane. Human ortholog(s) of this gene implicated in several diseases, including Leber hereditary optic neuropathy; anemia (multiple); hematologic cancer (multiple); respiratory system disease (multiple); and toxic encephalopathy. Orthologous to human EPHX1 (epoxide hydrolase 1). [provided by Alliance of Genome Resources, Nov 2024]
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Annotation release	Status	Assembly	Chr	Location
101	current	Xenopus_laevis_v10.1 (GCF_017654675.1)	5L	NC_054379.1 (17779633..17800598)
100	previous assembly	Xenopus_laevis_v2 (GCF_001663975.1)	5L	NC_030732.1 (17082690..17103981)

Chromosome 5L - NC_054379.1 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Submit: New GeneRIF Correction

Function	Evidence Code	Pubs
enables cis-stilbene-oxide hydrolase activity	IEA Inferred from Electronic Annotation more info
enables epoxide hydrolase activity	IEA Inferred from Electronic Annotation more info
enables ether hydrolase activity	IEA Inferred from Electronic Annotation more info
enables hydrolase activity	IEA Inferred from Electronic Annotation more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within catabolic process	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within epoxide metabolic process	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in endoplasmic reticulum	IEA Inferred from Electronic Annotation more info
located_in endoplasmic reticulum membrane	IEA Inferred from Electronic Annotation more info
located_in membrane	IEA Inferred from Electronic Annotation more info

Preferred Names: epoxide hydrolase 1; epoxide hydrolase 1, microsomal (xenobiotic) L homeolog

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The following sections contain reference sequences that belong to a specific genome build. Explain

The following Reference Sequences have been suppressed. Explain

NM_001091564.1: Suppressed sequence

Description

NM_001091564.1: This RefSeq was removed because it is a nonsense-mediated mRNA decay (NMD) candidate.