pbx2.L pre-B-cell leukemia homeobox 2 L homeolog [Xenopus laevis (African clawed frog)] - Gene

Summary

Official Symbol: pbx2.L
Official Full Name: pre-B-cell leukemia homeobox 2 L homeolog
Primary source: Xenbase:XB-GENE-865111
Locus tag: XELAEV_18039151mg
See related: EnsemblRapid:ENSXLAG00005024219 AllianceGenome:Xenbase:XB-GENE-865111
Gene type: protein coding
RefSeq status: MODEL
Organism: Xenopus laevis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as: pbx2; hox12; pbx2mhc
Summary: Predicted to enable chromatin binding activity. Predicted to act upstream of or within positive regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Predicted to be part of transcription regulator complex. Orthologous to human PBX2 (PBX homeobox 2). [provided by Alliance of Genome Resources, Nov 2024]
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Annotation release	Status	Assembly	Chr	Location
101	current	Xenopus_laevis_v10.1 (GCF_017654675.1)	8L	NC_054385.1 (65088123..65105607)
100	previous assembly	Xenopus_laevis_v2 (GCF_001663975.1)	8L	NC_030738.1 (51590538..51608115)

Chromosome 8L - NC_054385.1 Genomic Context describing neighboring genes

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

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Function	Evidence Code	Pubs
enables DNA binding	IEA Inferred from Electronic Annotation more info
enables DNA-binding transcription factor activity, RNA polymerase II-specific	IEA Inferred from Electronic Annotation more info
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding	IEA Inferred from Electronic Annotation more info
enables chromatin binding	ISS Inferred from Sequence or Structural Similarity more info

Process	Evidence Code	Pubs
acts_upstream_of_or_within animal organ development	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within animal organ morphogenesis	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within brain development	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within embryonic organ development	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within eye development	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within neuron development	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within positive regulation of transcription by RNA polymerase II	ISS Inferred from Sequence or Structural Similarity more info
acts_upstream_of_or_within regulation of DNA-templated transcription	IEA Inferred from Electronic Annotation more info
acts_upstream_of_or_within regulation of transcription by RNA polymerase II	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in nucleus	IEA Inferred from Electronic Annotation more info
located_in nucleus	ISS Inferred from Sequence or Structural Similarity more info
part_of transcription regulator complex	ISS Inferred from Sequence or Structural Similarity more info

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The following sections contain reference sequences that belong to a specific genome build. Explain

XM_041572866.1 → XP_041428800.1 pre-B-cell leukemia transcription factor 2 isoform X3

UniProtKB/Swiss-Prot

Q6IR52

UniProtKB/TrEMBL

A0A8J1LJD7
XM_018228844.2 → XP_018084333.1 pre-B-cell leukemia transcription factor 2 isoform X2

UniProtKB/TrEMBL

A0A8J0THC6
XM_018228843.2 → XP_018084332.1 pre-B-cell leukemia transcription factor 2 isoform X1

UniProtKB/TrEMBL

A0A1L8F8E1, A0A974H7W5

Related

ENSXLAP00005071745.1, ENSXLAT00005073292.1

The following Reference Sequences have been suppressed. Explain

NM_001091544.1: Suppressed sequence

Description

NM_001091544.1: This RefSeq was removed because it is a nonsense-mediated mRNA decay (NMD) candidate.