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nans.S N-acetylneuraminate synthase S homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 432051, updated on 4-Nov-2024

Summary

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Official Symbol
nans.S
Official Full Name
N-acetylneuraminate synthase S homeolog
Primary source
Xenbase:XB-GENE-17334261
Locus tag
XELAEV_18001214mg
See related
EnsemblRapid:ENSXLAG00005016553 AllianceGenome:Xenbase:XB-GENE-17334261
Gene type
protein coding
RefSeq status
PREDICTED
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Summary
Predicted to enable N-acylneuraminate-9-phosphate synthase activity. Predicted to act upstream of or within carbohydrate biosynthetic process and glycosylation. Human ortholog(s) of this gene implicated in spondyloepimetaphyseal dysplasia, Genevieve-type. Orthologous to human NANS (N-acetylneuraminate synthase). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See nans.S in Genome Data Viewer
Location:
chromosome: 1S
Exon count:
6
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 1S NC_054372.1 (100155387..100172777, complement)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) Unplaced Scaffold NW_016694812.1 (4399346..4416736)

Chromosome 1S - NC_054372.1Genomic Context describing neighboring genes Neighboring gene ring finger protein 38 S homeolog Neighboring gene tripartite motif containing 14 S homeolog Neighboring gene cyclin-O protein B-like Neighboring gene coronin-2A-like Neighboring gene guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase MESH1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Clone Names

  • MGC83164

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables N-acylneuraminate-9-phosphate synthase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within carbohydrate biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within glycosylation IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
uncharacterized protein LOC432051

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001091520.1 → NP_001084989.1  uncharacterized protein LOC432051

    See identical proteins and their annotated locations for NP_001084989.1

    Status: PREDICTED

    Source sequence(s)
    BC070693
    UniProtKB/TrEMBL
    Q6IRP2
    Related
    ENSXLAP00005048670.1, ENSXLAT00005049806.1
    Conserved Domains (3) summary
    cd11615
    Location:292 → 350
    SAF_NeuB_like; C-terminal SAF domain of sialic acid synthetase
    TIGR03569
    Location:19 → 343
    NeuB_NnaB; N-acetylneuraminate synthase
    pfam03102
    Location:40 → 278
    NeuB; NeuB family

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054372.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    100155387..100172777 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

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