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pheta2.L PH domain containing endocytic trafficking adaptor 2 L homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 431987, updated on 4-Nov-2024

Summary

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Official Symbol
pheta2.L
Official Full Name
PH domain containing endocytic trafficking adaptor 2 L homeolog
Primary source
Xenbase:XB-GENE-985682
Locus tag
XELAEV_18023546mg
See related
EnsemblRapid:ENSXLAG00005026644 AllianceGenome:Xenbase:XB-GENE-985682
Gene type
protein coding
RefSeq status
PREDICTED
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
ses2; fam109b; fam109b.L
Summary
Predicted to act upstream of or within endosome organization; receptor recycling; and retrograde transport, endosome to Golgi. Predicted to be located in cytoplasmic vesicle and trans-Golgi network. Is expressed in musculoskeletal system; nervous system; vestibuloauditory system; and visual system. Orthologous to human PHETA2 (PH domain containing endocytic trafficking adaptor 2). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See pheta2.L in Genome Data Viewer
Location:
chromosome: 4L
Exon count:
4
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 4L NC_054377.1 (112794512..112811340, complement)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 4L NC_030730.1 (107541339..107558200, complement)

Chromosome 4L - NC_054377.1Genomic Context describing neighboring genes Neighboring gene single-pass membrane protein with aspartate-rich tail 1 L homeolog Neighboring gene CCAAT enhancer binding protein gamma L homeolog Neighboring gene septin 3 L homeolog Neighboring gene centromere protein M L homeolog

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Clone Names

  • MGC81523

Gene Ontology Provided by Xenbase

Process Evidence Code Pubs
acts_upstream_of_or_within endosome organization IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within receptor recycling IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within retrograde transport, endosome to Golgi IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in Golgi apparatus IEA
Inferred from Electronic Annotation
more info
  
located_in clathrin-coated vesicle IEA
Inferred from Electronic Annotation
more info
  
located_in early endosome IEA
Inferred from Electronic Annotation
more info
  
located_in endosome IEA
Inferred from Electronic Annotation
more info
  
located_in recycling endosome IEA
Inferred from Electronic Annotation
more info
  
located_in trans-Golgi network IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
uncharacterized protein LOC431987
Names
family with sequence similarity 109 member B L homeolog
family with sequence similarity 109, member B

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001091461.1 → NP_001084930.1  uncharacterized protein LOC431987

    See identical proteins and their annotated locations for NP_001084930.1

    Status: PREDICTED

    Source sequence(s)
    BC070645
    UniProtKB/TrEMBL
    Q6NRS7
    Related
    ENSXLAP00005079246.1, ENSXLAT00005080837.1
    Conserved Domains (2) summary
    cd13288
    Location:4 → 123
    PH_Ses; Sesquipedalian family Pleckstrin homology (PH) domain
    pfam00169
    Location:15 → 105
    PH; PH domain

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054377.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    112794512..112811340 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_041589238.1 → XP_041445172.1  uncharacterized protein LOC431987 isoform X1

    UniProtKB/TrEMBL
    A0A1L8GNH6, A0A974D4L9
    Conserved Domains (1) summary
    cd13288
    Location:11 → 130
    PH_Ses; Sesquipedalian family Pleckstrin homology (PH) domain

  2. XM_018256629.2 → XP_018112118.1  uncharacterized protein LOC431987 isoform X1

    UniProtKB/TrEMBL
    A0A1L8GNH6, A0A974D4L9
    Related
    ENSXLAP00005079298.1, ENSXLAT00005080889.1
    Conserved Domains (1) summary
    cd13288
    Location:11 → 130
    PH_Ses; Sesquipedalian family Pleckstrin homology (PH) domain

  3. XM_018256630.2 → XP_018112119.1  uncharacterized protein LOC431987 isoform X1

    UniProtKB/TrEMBL
    A0A1L8GNH6, A0A974D4L9
    Conserved Domains (1) summary
    cd13288
    Location:11 → 130
    PH_Ses; Sesquipedalian family Pleckstrin homology (PH) domain

  4. XM_041589237.1 → XP_041445171.1  uncharacterized protein LOC431987 isoform X1

    UniProtKB/TrEMBL
    A0A1L8GNH6, A0A974D4L9
    Related
    ENSXLAP00005079195.1, ENSXLAT00005080786.1
    Conserved Domains (1) summary
    cd13288
    Location:11 → 130
    PH_Ses; Sesquipedalian family Pleckstrin homology (PH) domain

  5. XM_041589239.1 → XP_041445173.1  uncharacterized protein LOC431987 isoform X1

    UniProtKB/TrEMBL
    A0A1L8GNH6, A0A974D4L9
    Conserved Domains (1) summary
    cd13288
    Location:11 → 130
    PH_Ses; Sesquipedalian family Pleckstrin homology (PH) domain
Nucleotide Protein Strain
Heading Accession and Version

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