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nde1.S nudE neurodevelopment protein 1 S homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 431961, updated on 4-Nov-2024

Summary

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Official Symbol
nde1.S
Official Full Name
nudE neurodevelopment protein 1 S homeolog
Primary source
Xenbase:XB-GENE-1005621
Locus tag
XELAEV_18047509mg
See related
EnsemblRapid:ENSXLAG00005015621 AllianceGenome:Xenbase:XB-GENE-1005621
Gene type
protein coding
RefSeq status
MODEL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
mp43; nde1; nude; nude1; nde1-a; nde1-b
Summary
Predicted to enable microtubule binding activity. Predicted to act upstream of or within centrosome duplication. Predicted to be located in spindle pole centrosome. Predicted to be part of kinesin complex. Human ortholog(s) of this gene implicated in lissencephaly 4. Orthologous to human NDE1 (nudE neurodevelopment protein 1). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See nde1.S in Genome Data Viewer
Location:
chromosome: 9_10S
Exon count:
10
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 9_10S NC_054388.1 (88737397..88755499)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 9_10S NC_030741.1 (82066487..82082141)

Chromosome 9_10S - NC_054388.1Genomic Context describing neighboring genes Neighboring gene bMERB domain containing 1 S homeolog Neighboring gene meiosis regulator and mRNA stability factor 1 S homeolog Neighboring gene myosin heavy chain 11 S homeolog Neighboring gene NODAL modulator 3 S homeolog

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Identification of the laminar-inducing factor: Wnt-signal from the anterior rim induces correct laminar formation of the neural retina in vitro. Nakagawa S, et al. Dev Biol, 2003 Aug 15. PMID 12921742
  2. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  3. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Clone Names

  • MGC83772

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables microtubule binding IEA
Inferred from Electronic Annotation
more info
  
enables microtubule binding ISS
Inferred from Sequence or Structural Similarity
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within cell division IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within cell migration IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within centrosome duplication ISS
Inferred from Sequence or Structural Similarity
more info
  
acts_upstream_of_or_within centrosome localization IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within chromosome segregation IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within establishment of chromosome localization IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within establishment of mitotic spindle orientation IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within microtubule nucleation IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within mitotic centrosome separation IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within retina layer formation TAS
Traceable Author Statement
more info
 PubMed 
acts_upstream_of_or_within vesicle transport along microtubule IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in centrosome IEA
Inferred from Electronic Annotation
more info
  
located_in centrosome TAS
Traceable Author Statement
more info
 PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
  
located_in cytoplasm TAS
Traceable Author Statement
more info
 PubMed 
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
  
part_of kinesin complex IEA
Inferred from Electronic Annotation
more info
  
located_in kinetochore IEA
Inferred from Electronic Annotation
more info
  
located_in microtubule IEA
Inferred from Electronic Annotation
more info
  
located_in spindle IEA
Inferred from Electronic Annotation
more info
  
located_in spindle pole centrosome ISS
Inferred from Sequence or Structural Similarity
more info
  

General protein information

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Preferred Names
nuclear distribution protein nudE homolog 1-B
Names
Nuclear distribution protein nudE homolog 1-B
nudE nuclear distribution E homolog 1
nudE nuclear distribution gene E homolog 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054388.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    88737397..88755499
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_041579151.1 → XP_041435085.1  nuclear distribution protein nudE homolog 1-B

    UniProtKB/Swiss-Prot
    Q6NRJ5
    UniProtKB/TrEMBL
    A0A1L8EQ59, A0A974BUW9
    Related
    ENSXLAP00005045881.1, ENSXLAT00005046980.1
    Conserved Domains (2) summary
    TIGR02168
    Location:31 → 209
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam04880
    Location:135 → 300
    NUDE_C; NUDE protein, C-terminal conserved region

  2. XM_018237413.2 → XP_018092902.1  nuclear distribution protein nudE homolog 1-B

    UniProtKB/Swiss-Prot
    Q6NRJ5
    UniProtKB/TrEMBL
    A0A1L8EQ59, A0A974BUW9
    Conserved Domains (2) summary
    TIGR02168
    Location:31 → 209
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam04880
    Location:135 → 300
    NUDE_C; NUDE protein, C-terminal conserved region

  3. XM_018237412.2 → XP_018092901.1  nuclear distribution protein nudE homolog 1-B

    UniProtKB/Swiss-Prot
    Q6NRJ5
    UniProtKB/TrEMBL
    A0A1L8EQ59, A0A974BUW9
    Related
    ENSXLAP00005045868.1, ENSXLAT00005046967.1
    Conserved Domains (2) summary
    TIGR02168
    Location:31 → 209
    SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    pfam04880
    Location:135 → 300
    NUDE_C; NUDE protein, C-terminal conserved region

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_001091441.1: Suppressed sequence

    Description
    NM_001091441.1: This RefSeq was removed because it is a nonsense-mediated mRNA decay (NMD) candidate.
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q6NRJ5.2 GenPept UniProtKB/Swiss-Prot:Q6NRJ5

Gene LinkOut

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