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gramd1c.L GRAM domain containing 1C L homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 431948, updated on 4-Nov-2024

Summary

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Official Symbol
gramd1c.L
Official Full Name
GRAM domain containing 1C L homeolog
Primary source
Xenbase:XB-GENE-5944328
Locus tag
XELAEV_18011282mg
See related
EnsemblRapid:ENSXLAG00005029435 AllianceGenome:Xenbase:XB-GENE-5944328
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
gramd1c
Summary
Predicted to enable cholesterol binding activity and cholesterol transfer activity. Predicted to act upstream of or within intracellular sterol transport. Predicted to be located in endoplasmic reticulum membrane; endoplasmic reticulum-plasma membrane contact site; and plasma membrane. Orthologous to human GRAMD1C (GRAM domain containing 1C). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See gramd1c.L in Genome Data Viewer
Location:
chromosome: 2L
Exon count:
22
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 2L NC_054373.1 (2645983..2730436)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 2L NC_030726.1 (2690916..2746487)

Chromosome 2L - NC_054373.1Genomic Context describing neighboring genes Neighboring gene lamina-associated polypeptide 2 Neighboring gene N(alpha)-acetyltransferase 50, NatE catalytic subunit L homeolog Neighboring gene ATPase H+ transporting V1 subunit A L homeolog Neighboring gene uncharacterized LOC121399793 Neighboring gene protein Aster-C-like Neighboring gene uncharacterized LOC121399794

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Clone Names

  • MGC83836

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables cholesterol binding IEA
Inferred from Electronic Annotation
more info
  
enables cholesterol transfer activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within intracellular sterol transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in endoplasmic reticulum membrane IEA
Inferred from Electronic Annotation
more info
  
located_in endoplasmic reticulum-plasma membrane contact site IEA
Inferred from Electronic Annotation
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
GRAM domain containing 1C L homeolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001091428.1 → NP_001084897.2  GRAM domain containing 1C L homeolog

    Status: PROVISIONAL

    Source sequence(s)
    BC070790
    UniProtKB/TrEMBL
    A0A8J0PUR3, A0A974DKC6
    Conserved Domains (1) summary
    pfam16016
    Location:130 → 276
    DUF4782; Domain of unknown function (DUF4782)

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054373.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    2645983..2730436
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_041580942.1 → XP_041436876.1  GRAM domain containing 1C L homeolog isoform X1

    UniProtKB/TrEMBL
    A0A8J1M6E2, A0A974DKY3
    Related
    ENSXLAP00005088765.1, ENSXLAT00005090434.1
    Conserved Domains (1) summary
    cd13220
    Location:76 → 169
    PH-GRAM_GRAMDC; GRAM domain-containing protein (GRAMDC) Pleckstrin Homology-Glucosyltransferases, Rab-like GTPase activators and Myotubularins (PH-GRAM) domain

  2. XM_041580943.1 → XP_041436877.1  GRAM domain containing 1C L homeolog isoform X2

    UniProtKB/TrEMBL
    A0A8J1M5B1, A0A974DKY3
    Related
    ENSXLAP00005088002.1, ENSXLAT00005089664.1
    Conserved Domains (1) summary
    cd13220
    Location:60 → 153
    PH-GRAM_GRAMDC; GRAM domain-containing protein (GRAMDC) Pleckstrin Homology-Glucosyltransferases, Rab-like GTPase activators and Myotubularins (PH-GRAM) domain

  3. XM_041580944.1 → XP_041436878.1  GRAM domain containing 1C L homeolog isoform X3

    UniProtKB/TrEMBL
    A0A8J1M5B4, A0A974DKY3
    Conserved Domains (1) summary
    cd13220
    Location:46 → 139
    PH-GRAM_GRAMDC; GRAM domain-containing protein (GRAMDC) Pleckstrin Homology-Glucosyltransferases, Rab-like GTPase activators and Myotubularins (PH-GRAM) domain
Nucleotide Protein Strain
Heading Accession and Version

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