pals2.S protein associated with LIN7 2, MAGUK p55 family member S homeolog [Xenopus laevis (African clawed frog)] - Gene

Summary

Official Symbol: pals2.S
Official Full Name: protein associated with LIN7 2, MAGUK p55 family member S homeolog
Primary source: Xenbase:XB-GENE-983257
Locus tag: XELAEV_18033057mg
See related: EnsemblRapid:ENSXLAG00005003864 AllianceGenome:Xenbase:XB-GENE-983257
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Xenopus laevis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as: mpp6; p55t; vam1; vam-1; mpp6.S
Summary: Predicted to be located in cell-cell junction and plasma membrane. Orthologous to human PALS2 (protein associated with LIN7 2, MAGUK p55 family member). [provided by Alliance of Genome Resources, Nov 2024]
Annotation information: Annotation category: partial on reference assembly
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Genomic context

Location:: chromosome: 6S

Exon count:: 12

Annotation release	Status	Assembly	Chr	Location
101	current	Xenopus_laevis_v10.1 (GCF_017654675.1)	6S	NC_054382.1 (33429857..33469425)
100	previous assembly	Xenopus_laevis_v2 (GCF_001663975.1)	6S	NC_030735.1 (32521358..32561073)

Chromosome 6S - NC_054382.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Gene Ontology Provided by Xenbase

Component	Evidence Code	Pubs
located_in cell-cell junction	IEA Inferred from Electronic Annotation more info
located_in plasma membrane	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: protein associated with LIN7 2, MAGUK p55 family member S homeolog

Names: membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6); membrane protein, palmitoylated 6 S homeolog; protein associated with LIN7 2, MAGUK family member S homeolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001091314.1 → NP_001084783.1 protein associated with LIN7 2, MAGUK p55 family member S homeolog

See identical proteins and their annotated locations for NP_001084783.1

Status: PROVISIONAL

Source sequence(s)

BC070576

UniProtKB/TrEMBL

A0A974CIV0, Q6NRY3

Related

ENSXLAP00005011535.1, ENSXLAT00005011709.1

Conserved Domains (6) summary

smart00569
Location:2 → 55

L27; domain in receptor targeting proteins Lin-2 and Lin-7

cd12038
Location:217 → 277

SH3_MPP6; Src Homology 3 domain of Membrane Protein, Palmitoylated 6 (or MAGUK p55 subfamily member 6)

smart00072
Location:345 → 523

GuKc; Guanylate kinase homologues

cd00992
Location:126 → 204

PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...

pfam00625
Location:335 → 522

Guanylate_kin; Guanylate kinase

pfam02828
Location:57 → 108

L27; L27 domain