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Npl4 - Nuclear protein localization 4

Enables K11-linked polyubiquitin modification-dependent protein binding activity. Involved in cellular response to virus; negative regulation of smoothened signaling pathway; and ubiquitin-dependent protein catabolic process. Located in cytosol and nucleoplasm. Is expressed in adult head and adult heart. Used to study neurodegenerative disease. Orthologous to human NPLOC4 (NPL4 homolog, ubiquitin recognition factor). [provided by Alliance of Genome Resources, Apr 2022]

Genes similar to Npl4

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Species Gene Architecture aa