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NEU3 neuraminidase 3 [ Gallus gallus (chicken) ]

Gene ID: 430542, updated on 3-Apr-2024

Summary

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Official Symbol
NEU3provided by CGNC
Official Full Name
neuraminidase 3provided by CGNC
Primary source
CGNC:66584
See related
Ensembl:ENSGALG00010001886
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 1
Exon count:
5
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 1 NC_052532.1 (194739342..194744054)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 1 NC_052573.1 (194608392..194612480)

Chromosome 1 - NC_052532.1Genomic Context describing neighboring genes Neighboring gene chordin like 2 Neighboring gene ring finger protein 169 Neighboring gene X-ray radiation resistance associated 1 Neighboring gene signal peptidase complex subunit 2 Neighboring gene prolyl 4-hydroxylase subunit alpha 3 Neighboring gene protein phosphatase methylesterase 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Gallus gallus NEU3 sialidase as model to study protein evolution mechanism based on rapid evolving loops. Giacopuzzi E, et al. BMC Biochem, 2011 Aug 23. PMID 21861893, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. features of the evolving loops in NEU3
    Title: Gallus gallus NEU3 sialidase as model to study protein evolution mechanism based on rapid evolving loops.
Submit: New GeneRIF Correction

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables exo-alpha-sialidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in ganglioside catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in oligosaccharide catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in lysosome IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
sialidase-3
Names
membrane-bound sialidase
sialidase 3 (membrane sialidase)
NP_001305946.3
XP_015136494.2
XP_015136495.2
XP_015136497.2
XP_040557624.1
XP_046764558.1
XP_046764559.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001319017.3 → NP_001305946.3  sialidase-3

    Status: VALIDATED

    Source sequence(s)
    JAENSK010000032
    UniProtKB/TrEMBL
    G4V263
    Conserved Domains (1) summary
    cd15482
    Location:30 → 344
    Sialidase_non-viral; Non-viral sialidases

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052532.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    194739342..194744054
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015281008.4 → XP_015136494.2  sialidase-3 isoform X3

    UniProtKB/TrEMBL
    A0A8V0X3Z6, A0A8V0X7I5
    Related
    ENSGALP00010002597.1, ENSGALT00010004309.1
    Conserved Domains (1) summary
    cd15482
    Location:43 → 357
    Sialidase_non-viral; Non-viral sialidases

  2. XM_015281011.3 → XP_015136497.2  sialidase-3 isoform X1

    UniProtKB/TrEMBL
    G4V263
    Conserved Domains (1) summary
    cd15482
    Location:30 → 344
    Sialidase_non-viral; Non-viral sialidases

  3. XM_040701690.2 → XP_040557624.1  sialidase-3 isoform X4

    UniProtKB/TrEMBL
    A0A8V0X7I5
    Conserved Domains (1) summary
    cd15482
    Location:58 → 372
    Sialidase_non-viral; Non-viral sialidases

  4. XM_015281009.4 → XP_015136495.2  sialidase-3 isoform X2

    UniProtKB/TrEMBL
    G4V263
    Conserved Domains (1) summary
    cd15482
    Location:58 → 372
    Sialidase_non-viral; Non-viral sialidases

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052573.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    194608392..194612480
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046908602.1 → XP_046764558.1  sialidase-3 isoform X1

  2. XM_046908603.1 → XP_046764559.1  sialidase-3 isoform X5

Nucleotide Protein
Heading Accession and Version

Gene LinkOut

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