ASCL2 - achaete-scute family bHLH transcription factor 2
This gene is a member of the basic helix-loop-helix (BHLH) family of transcription factors. It activates transcription by binding to the E box (5'-CANNTG-3'). Dimerization with other BHLH proteins is required for efficient DNA binding. Involved in the determination of the neuronal precursors in the peripheral nervous system and the central nervous system. [provided by RefSeq, Jul 2008]
NCBI Orthologs
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Protein alignment
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Species | Gene | Architecture | aa |
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