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MTRR 5-methyltetrahydrofolate-homocysteine methyltransferase reductase [ Gallus gallus (chicken) ]

Gene ID: 428502, updated on 17-Aug-2024

Summary

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Symbol
MTRRprovided by CGNC
Full Name
5-methyltetrahydrofolate-homocysteine methyltransferase reductaseprovided by CGNC
Primary source
CGNC:9870
See related
Ensembl:ENSGALG00010000803
Gene type
protein coding
RefSeq status
MODEL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs
human mouse all
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Genomic context

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See MTRR in Genome Data Viewer
Location:
chromosome: 2
Exon count:
16
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 2 NC_052533.1 (78832279..78859335, complement)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 2 NC_052574.1 (78831337..78858390, complement)

Chromosome 2 - NC_052533.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC121109637 Neighboring gene uncharacterized LOC112531793 Neighboring gene FAST kinase domains 3 Neighboring gene chromosome 5 open reading frame 49 Neighboring gene adenylate cyclase 2 Neighboring gene SUN domain-containing protein 3-like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  2. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables FMN binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables [methionine synthase] reductase (NADPH) activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables flavin adenine dinucleotide binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in homocysteine metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in methionine biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
methionine synthase reductase
XP_004935186.3
XP_040519319.1
XP_040519320.1
XP_426057.5

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052533.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    78832279..78859335 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_426057.8 → XP_426057.5  methionine synthase reductase

    UniProtKB/TrEMBL
    A0A8V0X6E4
    Related
    ENSGALP00010000964.1, ENSGALT00010001763.1
    Conserved Domains (2) summary
    cd06203
    Location:273 → 692
    methionine_synthase_red; Human methionine synthase reductase (MSR) restores methionine sythase which is responsible for the regeneration of methionine from homocysteine, as well as the coversion of methyltetrahydrofolate to tetrahydrofolate. In MSR, electrons are transferred ...
    cl00438
    Location:11 → 155
    FMN_red; NADPH-dependent FMN reductase

  2. XM_004935129.5 → XP_004935186.3  methionine synthase reductase

    UniProtKB/TrEMBL
    A0A8V0X6E4
    Conserved Domains (2) summary
    cd06203
    Location:273 → 692
    methionine_synthase_red; Human methionine synthase reductase (MSR) restores methionine sythase which is responsible for the regeneration of methionine from homocysteine, as well as the coversion of methyltetrahydrofolate to tetrahydrofolate. In MSR, electrons are transferred ...
    cl00438
    Location:11 → 155
    FMN_red; NADPH-dependent FMN reductase

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052574.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    78831337..78858390 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040663385.2 → XP_040519319.1  methionine synthase reductase

    UniProtKB/TrEMBL
    A0A8V0X6E4
    Conserved Domains (2) summary
    cd06203
    Location:273 → 692
    methionine_synthase_red; Human methionine synthase reductase (MSR) restores methionine sythase which is responsible for the regeneration of methionine from homocysteine, as well as the coversion of methyltetrahydrofolate to tetrahydrofolate. In MSR, electrons are transferred ...
    cl00438
    Location:11 → 155
    FMN_red; NADPH-dependent FMN reductase

  2. XM_040663386.2 → XP_040519320.1  methionine synthase reductase

    UniProtKB/TrEMBL
    A0A8V0X6E4
    Conserved Domains (2) summary
    cd06203
    Location:273 → 692
    methionine_synthase_red; Human methionine synthase reductase (MSR) restores methionine sythase which is responsible for the regeneration of methionine from homocysteine, as well as the coversion of methyltetrahydrofolate to tetrahydrofolate. In MSR, electrons are transferred ...
    cl00438
    Location:11 → 155
    FMN_red; NADPH-dependent FMN reductase
Nucleotide Protein Strain
Heading Accession and Version

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