SIRT6 sirtuin 6 [Gallus gallus (chicken)] - Gene

Summary

Symbol: SIRT6provided by CGNC
Full Name: sirtuin 6provided by CGNC
Primary source: CGNC:850
See related: Ensembl:ENSGALG00010027223
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Gallus gallus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 28

Exon count:: 8

Annotation release	Status	Assembly	Chr	Location
106	current	bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2)	28	NC_052559.1 (3035809..3041831)
106	current	bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2)	28	NC_052600.1 (2601917..2607938)

Chromosome 28 - NC_052559.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Data show that the expression levels of cSIRT1, cSIRT2, cSIRT4, cSIRT6, and cSIRT7 in the liver increased significantly with sexual maturity.
Title: Characteristics of expression and regulation of sirtuins in chicken (Gallus gallus).

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General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables NAD+ binding	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: NAD-dependent protein deacylase sirtuin-6

Names: NAD-dependent deacetylase sirtuin-6; NAD-dependent protein deacetylase sirtuin-6

NP_001034409.2

EC 3.5.1.-

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001039320.2 → NP_001034409.2 NAD-dependent protein deacylase sirtuin-6

Status: PROVISIONAL

Source sequence(s)

JAENSK010000375

UniProtKB/TrEMBL

F1P0C4, Q5ZMR8

Related

ENSGALP00010040267.1, ENSGALT00010066001.1

Conserved Domains (1) summary

cd01410
Location:47 → 257

SIRT7; Eukaryotic and prokaryotic group (class4) which includes human sirtuin SIRT6, SIRT7, and several bacterial homologs; and are members of the SIR2 family of proteins, silent information regulator 2 (Sir2) enzymes which catalyze NAD+-dependent protein ...