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NRG2 neuregulin 2 [ Gallus gallus (chicken) ]

Gene ID: 427606, updated on 17-Aug-2024

Summary

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Symbol
NRG2provided by CGNC
Full Name
neuregulin 2provided by CGNC
Primary source
CGNC:611
See related
Ensembl:ENSGALG00010011853
Gene type
protein coding
RefSeq status
MODEL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs
human mouse all
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Genomic context

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See NRG2 in Genome Data Viewer
Location:
chromosome: 13
Exon count:
14
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 13 NC_052544.1 (405138..559030)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 13 NC_052585.1 (612875..766429)

Chromosome 13 - NC_052544.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC107054478 Neighboring gene prefoldin subunit 1 Neighboring gene cysteine rich transmembrane module containing 1 Neighboring gene purine rich element binding protein A Neighboring gene uncharacterized LOC112533401 Neighboring gene pleckstrin and Sec7 domain containing 2 Neighboring gene uncharacterized LOC121106714

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables signaling receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in animal organ development IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in nervous system development IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
pro-neuregulin-2, membrane-bound isoform

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052544.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    405138..559030
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015293545.4 → XP_015149031.1  pro-neuregulin-2, membrane-bound isoform isoform X2

    UniProtKB/TrEMBL
    A0A1D5P4M3
    Conserved Domains (2) summary
    pfam02158
    Location:362 → 721
    Neuregulin; Neuregulin family
    cd05750
    Location:147 → 238
    Ig_Pro_neuregulin; Immunoglobulin (Ig)-like domain in neuregulins

  2. XM_015293544.4 → XP_015149030.1  pro-neuregulin-2, membrane-bound isoform isoform X1

    UniProtKB/TrEMBL
    A0A1D5P4M3
    Conserved Domains (3) summary
    PHA03099
    Location:275 → 357
    PHA03099; epidermal growth factor-like protein (EGF-like protein); Provisional
    pfam02158
    Location:364 → 723
    Neuregulin; Neuregulin family
    cd05750
    Location:147 → 238
    Ig_Pro_neuregulin; Immunoglobulin (Ig)-like domain in neuregulins

  3. XM_015293546.4 → XP_015149032.1  pro-neuregulin-2, membrane-bound isoform isoform X3

    UniProtKB/TrEMBL
    A0A1D5P4M3
    Conserved Domains (3) summary
    PHA03099
    Location:275 → 349
    PHA03099; epidermal growth factor-like protein (EGF-like protein); Provisional
    pfam02158
    Location:356 → 715
    Neuregulin; Neuregulin family
    cd05750
    Location:147 → 238
    Ig_Pro_neuregulin; Immunoglobulin (Ig)-like domain in neuregulins

  4. XM_015293547.4 → XP_015149033.1  pro-neuregulin-2, membrane-bound isoform isoform X4

    UniProtKB/TrEMBL
    A0A1D5P4M3, A0A1D5PVP0
    Related
    ENSGALP00010016211.1, ENSGALT00010028304.1
    Conserved Domains (3) summary
    PHA03099
    Location:253 → 301
    PHA03099; epidermal growth factor-like protein (EGF-like protein); Provisional
    pfam02158
    Location:342 → 701
    Neuregulin; Neuregulin family
    cd05750
    Location:147 → 238
    Ig_Pro_neuregulin; Immunoglobulin (Ig)-like domain in neuregulins

  5. XM_040647040.2 → XP_040502974.1  pro-neuregulin-2, membrane-bound isoform isoform X5

    Conserved Domains (2) summary
    smart00409
    Location:43 → 124
    IG; Immunoglobulin
    cd00054
    Location:149 → 177
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052585.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    612875..766429
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040682795.2 → XP_040538729.1  pro-neuregulin-2, membrane-bound isoform isoform X2

    UniProtKB/TrEMBL
    A0A1D5P4M3
    Conserved Domains (2) summary
    pfam02158
    Location:362 → 721
    Neuregulin; Neuregulin family
    cd05750
    Location:147 → 238
    Ig_Pro_neuregulin; Immunoglobulin (Ig)-like domain in neuregulins

  2. XM_040682794.2 → XP_040538728.1  pro-neuregulin-2, membrane-bound isoform isoform X1

    UniProtKB/TrEMBL
    A0A1D5P4M3
    Conserved Domains (3) summary
    PHA03099
    Location:275 → 357
    PHA03099; epidermal growth factor-like protein (EGF-like protein); Provisional
    pfam02158
    Location:364 → 723
    Neuregulin; Neuregulin family
    cd05750
    Location:147 → 238
    Ig_Pro_neuregulin; Immunoglobulin (Ig)-like domain in neuregulins

  3. XM_040682796.2 → XP_040538730.1  pro-neuregulin-2, membrane-bound isoform isoform X3

    UniProtKB/TrEMBL
    A0A1D5P4M3
    Conserved Domains (3) summary
    PHA03099
    Location:275 → 349
    PHA03099; epidermal growth factor-like protein (EGF-like protein); Provisional
    pfam02158
    Location:356 → 715
    Neuregulin; Neuregulin family
    cd05750
    Location:147 → 238
    Ig_Pro_neuregulin; Immunoglobulin (Ig)-like domain in neuregulins

  4. XM_040682797.2 → XP_040538731.1  pro-neuregulin-2, membrane-bound isoform isoform X4

    UniProtKB/TrEMBL
    A0A1D5P4M3, A0A1D5PVP0
    Conserved Domains (3) summary
    PHA03099
    Location:253 → 301
    PHA03099; epidermal growth factor-like protein (EGF-like protein); Provisional
    pfam02158
    Location:342 → 701
    Neuregulin; Neuregulin family
    cd05750
    Location:147 → 238
    Ig_Pro_neuregulin; Immunoglobulin (Ig)-like domain in neuregulins

  5. XM_040682798.2 → XP_040538732.1  pro-neuregulin-2, membrane-bound isoform isoform X5

    Conserved Domains (2) summary
    smart00409
    Location:43 → 124
    IG; Immunoglobulin
    cd00054
    Location:149 → 177
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
Nucleotide Protein Strain
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