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HAS3 hyaluronan synthase 3 [ Gallus gallus (chicken) ]

Gene ID: 427564, updated on 10-Oct-2024

Summary

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Symbol
HAS3provided by CGNC
Full Name
hyaluronan synthase 3provided by CGNC
Primary source
CGNC:394
See related
Ensembl:ENSGALG00010008156
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Also known as
CHAS3
Orthologs
human mouse all
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Genomic context

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See HAS3 in Genome Data Viewer
Location:
chromosome: 11
Exon count:
5
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 11 NC_052542.1 (18555132..18559819)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 11 NC_052583.1 (18903088..18907775)

Chromosome 11 - NC_052542.1Genomic Context describing neighboring genes Neighboring gene cadherin 1 Neighboring gene transmembrane and coiled-coil domains 7 Neighboring gene chromosome transmission fidelity factor 8 Neighboring gene UTP4, small subunit processome component

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Characterization and molecular evolution of a vertebrate hyaluronan synthase gene family. Spicer AP, et al. J Biol Chem, 1998 Jan 23. PMID 9442026
  2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables hyaluronan synthase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in extracellular matrix assembly IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in extracellular polysaccharide biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in hyaluronan biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
hyaluronan synthase 3
Names
HA synthase 3
hyaluronate synthase 3
hyaluronic acid synthase 3
NP_001383541.1
XP_040537117.1
XP_046755489.1
XP_046781662.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001396612.1 → NP_001383541.1  hyaluronan synthase 3

    Status: VALIDATED

    Source sequence(s)
    JAENSK010000248
    UniProtKB/Swiss-Prot
    F1NU27, O57425
    UniProtKB/TrEMBL
    A0A8V0Y0W2
    Related
    ENSGALP00010010998.1, ENSGALT00010019450.1
    Conserved Domains (1) summary
    cd06434
    Location:82 → 359
    GT2_HAS; Hyaluronan synthases catalyze polymerization of hyaluronan

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052542.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    18555132..18559819
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046899533.1 → XP_046755489.1  hyaluronan synthase 3 isoform X1

    UniProtKB/TrEMBL
    A0A8V0Y0W2

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052583.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    18903088..18907775
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040681183.2 → XP_040537117.1  hyaluronan synthase 3 isoform X2

    UniProtKB/Swiss-Prot
    F1NU27, O57425
    Conserved Domains (1) summary
    cd06434
    Location:120 → 397
    GT2_HAS; Hyaluronan synthases catalyze polymerization of hyaluronan

  2. XM_046925706.1 → XP_046781662.1  hyaluronan synthase 3 isoform X1

Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
O57425.2 GenPept UniProtKB/Swiss-Prot:O57425

Gene LinkOut

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Molecular Biology Databases
Research Materials