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cnc - cap-n-collar

Enables DNA-binding transcription activator activity, RNA polymerase II-specific and protein heterodimerization activity. Contributes to DNA-binding transcription factor activity. Involved in several processes, including determination of adult lifespan; oocyte axis specification; and regulation of intracellular mRNA localization. Located in nucleus and polytene chromosome puff. Is expressed in several structures, including adult brain; adult pars intercerebralis; antennal anlage; cuboidal/columnar epithelium; and head segment. Human ortholog(s) of this gene implicated in Alzheimer's disease; cataract; hepatocellular carcinoma; macular degeneration; and tuberculosis. Orthologous to several human genes including NFE2L1 (NFE2 like bZIP transcription factor 1); NFE2L2 (NFE2 like bZIP transcription factor 2); and NFE2L3 (NFE2 like bZIP transcription factor 3). [provided by Alliance of Genome Resources, Oct 2024]

Genes similar to cnc

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Species Gene Architecture aa