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PARP8 poly(ADP-ribose) polymerase family member 8 [ Gallus gallus (chicken) ]

Gene ID: 427198, updated on 18-Sep-2024

Summary

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Symbol
PARP8provided by CGNC
Full Name
poly(ADP-ribose) polymerase family member 8provided by CGNC
Primary source
CGNC:11045
See related
Ensembl:ENSGALG00010014014
Gene type
protein coding
RefSeq status
MODEL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs
human mouse all
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Genomic context

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See PARP8 in Genome Data Viewer
Location:
chromosome: Z
Exon count:
26
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) Z NC_052572.1 (15336798..15448633)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) Z NC_059536.1 (15336798..15448633)

Chromosome Z - NC_052572.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC121108358 Neighboring gene embigin Neighboring gene uncharacterized LOC121108497 Neighboring gene ISL LIM homeobox 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables NAD+-protein poly-ADP-ribosyltransferase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables kinase binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein serine/threonine kinase activator activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in endoplasmic reticulum unfolded protein response IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in endoplasmic reticulum tubular network IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in intracellular anatomical structure IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nuclear envelope IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
poly [ADP-ribose] polymerase 8; protein mono-ADP-ribosyltransferase PARP8
XP_040511981.1
XP_040511982.1
XP_046791486.1
XP_046791487.1
XP_046791488.1
XP_424786.3

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052572.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    15336798..15448633
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_424786.8 → XP_424786.3  protein mono-ADP-ribosyltransferase PARP8 isoform X1

    UniProtKB/TrEMBL
    A0A8V0YG18
    Related
    ENSGALP00010019803.1, ENSGALT00010033629.1
    Conserved Domains (1) summary
    cd01341
    Location:695 → 820
    ADP_ribosyl; ADP_ribosylating enzymes catalyze the transfer of ADP_ribose from NAD+ to substrates. Bacterial toxins are cytoplasmic and catalyze the transfer of a single ADP_ribose unit to eukaryotic elongation factor 2, halting protein synthesis and killing the cell. ...

  2. XM_040656047.2 → XP_040511981.1  protein mono-ADP-ribosyltransferase PARP8 isoform X2

    UniProtKB/TrEMBL
    A0A8V0YG18
    Conserved Domains (1) summary
    cd01341
    Location:549 → 674
    ADP_ribosyl; ADP_ribosylating enzymes catalyze the transfer of ADP_ribose from NAD+ to substrates. Bacterial toxins are cytoplasmic and catalyze the transfer of a single ADP_ribose unit to eukaryotic elongation factor 2, halting protein synthesis and killing the cell. ...

  3. XM_040656048.2 → XP_040511982.1  protein mono-ADP-ribosyltransferase PARP8 isoform X3

    UniProtKB/TrEMBL
    A0A8V0YG18
    Conserved Domains (1) summary
    cd01341
    Location:544 → 669
    ADP_ribosyl; ADP_ribosylating enzymes catalyze the transfer of ADP_ribose from NAD+ to substrates. Bacterial toxins are cytoplasmic and catalyze the transfer of a single ADP_ribose unit to eukaryotic elongation factor 2, halting protein synthesis and killing the cell. ...

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_059536.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    15336798..15448633
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046935530.1 → XP_046791486.1  protein mono-ADP-ribosyltransferase PARP8 isoform X1

    UniProtKB/TrEMBL
    A0A8V0YG18

  2. XM_046935531.1 → XP_046791487.1  protein mono-ADP-ribosyltransferase PARP8 isoform X2

    UniProtKB/TrEMBL
    A0A8V0YG18

  3. XM_046935532.1 → XP_046791488.1  protein mono-ADP-ribosyltransferase PARP8 isoform X3

    UniProtKB/TrEMBL
    A0A8V0YG18
Nucleotide Protein Strain
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