SUPT5H SPT5 homolog, DSIF elongation factor subunit [Gallus gallus (chicken)] - Gene

Summary

Symbol: SUPT5Hprovided by CGNC
Full Name: SPT5 homolog, DSIF elongation factor subunitprovided by CGNC
Primary source: CGNC:10651
See related: Ensembl:ENSGALG00010009047
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Gallus gallus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Annotation information: Annotation category: suggests misassembly; Annotation category: partial on reference assembly
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 38

Exon count:: 29

Annotation release	Status	Assembly	Chr	Location
106	current	bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2)	38	NC_052569.1 (1..7466, complement)
106	current	bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2)	38	NC_052610.1 (47798..55409, complement)

Chromosome 38 - NC_052569.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

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Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables mRNA binding	IEA Inferred from Electronic Annotation more info	PubMed
enables protein binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in regulation of DNA-templated transcription elongation	IEA Inferred from Electronic Annotation more info	PubMed
involved_in regulation of transcription by RNA polymerase II	IEA Inferred from Electronic Annotation more info	PubMed
involved_in transcription elongation by RNA polymerase II	IEA Inferred from Electronic Annotation more info	PubMed
involved_in transcription elongation-coupled chromatin remodeling	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
part_of DSIF complex	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: transcription elongation factor SPT5

Names: DRB sensitivity-inducing factor large subunit; DSIF large subunit; suppressor of Ty 5 homolog

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001031384.2 → NP_001026555.1 transcription elongation factor SPT5

See identical proteins and their annotated locations for NP_001026555.1

Status: VALIDATED

Source sequence(s)

JAENSL010000354

UniProtKB/Swiss-Prot

Q5ZI08

UniProtKB/TrEMBL

A0A8V0Y8F2

Related

ENSGALP00010012277.1, ENSGALT00010021553.1

Conserved Domains (13) summary

cd09888
Location:175 → 262

NGN_Euk; Eukaryotic N-Utilization Substance G (NusG) N-terminal (NGN) domain, including plant KTF1 (KOW domain-containing Transcription Factor 1)

smart01104
Location:764 → 881

CTD; Spt5 C-terminal nonapeptide repeat binding Spt4

COG0250
Location:173 → 314

NusG; Transcription antitermination factor NusG [Transcription]

cd06081
Location:273 → 310

KOW_Spt5_1; KOW domain of Spt5, repeat 1

cd06082
Location:417 → 467

KOW_Spt5_2; KOW domain of Spt5, repeat 2

cd06083
Location:468 → 518

KOW_Spt5_3; KOW domain of Spt5, repeat 3

cd06084
Location:594 → 636

KOW_Spt5_4; KOW domain of Spt5, repeat 4

cd06085
Location:694 → 743

KOW_Spt5_5; KOW domain of Spt5, repeat 5

cd06086
Location:1020 → 1076

KOW_Spt5_6; KOW domain of Spt5, repeat 6

pfam04731
Location:839 → 968

Caudal_act; Caudal like protein activation region

pfam11235
Location:840 → 1003

Med25_SD1; Mediator complex subunit 25 synapsin 1

pfam11942
Location:90 → 168

Spt5_N; Spt5 transcription elongation factor, acidic N-terminal

pfam12815
Location:758 → 814

CTD; Spt5 C-terminal nonapeptide repeat binding Spt4