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BCL6 B-cell CLL/lymphoma 6 [ Gallus gallus (chicken) ]

Gene ID: 424912, updated on 17-Aug-2024

Summary

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Symbol
BCL6provided by CGNC
Full Name
B-cell CLL/lymphoma 6provided by CGNC
Primary source
CGNC:5559
See related
Ensembl:ENSGALG00010013635
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs
human mouse all
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Genomic context

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See BCL6 in Genome Data Viewer
Location:
chromosome: 9
Exon count:
13
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 9 NC_052540.1 (14479373..14495601)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 9 NC_052581.1 (14275276..14291508)

Chromosome 9 - NC_052540.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC101751200 Neighboring gene uncharacterized LOC107054097 Neighboring gene somatostatin 1 Neighboring gene mannan binding lectin serine peptidase 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Alternate pathways for Bcl6-mediated regulation of B cell to plasma cell differentiation. Alinikula J, et al. Eur J Immunol, 2011 Aug. PMID 21674482
  2. STAT5 represses BCL6 expression by binding to a regulatory region frequently mutated in lymphomas. Walker SR, et al. Oncogene, 2007 Jan 11. PMID 16819511
  3. Bcl6 regulates Th2 type cytokine productions by mast cells activated by FcepsilonRI/IgE cross-linking. Ohtsuka Y, et al. Mol Immunol, 2005 Aug. PMID 15950739
  4. Abnormal erythroid differentiation in neonatal bcl-6-deficient mice. Asari S, et al. Exp Hematol, 2005 Jan. PMID 15661395
  5. BCL-6 negatively regulates expression of the NF-kappaB1 p105/p50 subunit. Li Z, et al. J Immunol, 2005 Jan 1. PMID 15611242

See all (24) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
B-cell lymphoma 6 protein homolog
Names
B-cell CLL/lymphoma 6 (zinc finger protein 51)

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001012930.1 → NP_001012948.1  B-cell lymphoma 6 protein homolog

    See identical proteins and their annotated locations for NP_001012948.1

    Status: PROVISIONAL

    Source sequence(s)
    AJ719545
    UniProtKB/Swiss-Prot
    Q5ZM39
    Related
    ENSGALP00010019424.1, ENSGALT00010032792.1
    Conserved Domains (4) summary
    smart00225
    Location:33 → 129
    BTB; Broad-Complex, Tramtrack and Bric a brac
    sd00017
    Location:578 → 598
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam00651
    Location:22 → 126
    BTB; BTB/POZ domain
    pfam13465
    Location:590 → 615
    zf-H2C2_2; Zinc-finger double domain

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052540.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    14479373..14495601
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015291406.4 → XP_015146892.2  B-cell lymphoma 6 protein homolog isoform X1

    UniProtKB/TrEMBL
    A0A8V0YN89
    Conserved Domains (3) summary
    COG5189
    Location:545 → 650
    SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
    sd00017
    Location:578 → 598
    ZF_C2H2; C2H2 Zn finger [structural motif]
    cd18331
    Location:8 → 125
    BTB_POZ_ZBTB27_BCL6; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in B-cell lymphoma 6 protein (BCL-6)

  2. XM_040705572.2 → XP_040561506.1  B-cell lymphoma 6 protein homolog isoform X1

    UniProtKB/TrEMBL
    A0A8V0YN89
    Conserved Domains (3) summary
    COG5189
    Location:545 → 650
    SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
    sd00017
    Location:578 → 598
    ZF_C2H2; C2H2 Zn finger [structural motif]
    cd18331
    Location:8 → 125
    BTB_POZ_ZBTB27_BCL6; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in B-cell lymphoma 6 protein (BCL-6)

  3. XM_025153369.3 → XP_025009137.2  B-cell lymphoma 6 protein homolog isoform X1

    UniProtKB/TrEMBL
    A0A8V0YN89
    Conserved Domains (3) summary
    COG5189
    Location:545 → 650
    SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
    sd00017
    Location:578 → 598
    ZF_C2H2; C2H2 Zn finger [structural motif]
    cd18331
    Location:8 → 125
    BTB_POZ_ZBTB27_BCL6; BTB (Broad-Complex, Tramtrack and Bric a brac)/POZ (poxvirus and zinc finger) domain found in B-cell lymphoma 6 protein (BCL-6)

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052581.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    14275276..14291508
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046923881.1 → XP_046779837.1  B-cell lymphoma 6 protein homolog isoform X1

    UniProtKB/TrEMBL
    A0A8V0YN89

  2. XM_046923883.1 → XP_046779839.1  B-cell lymphoma 6 protein homolog isoform X1

    UniProtKB/TrEMBL
    A0A8V0YN89

  3. XM_046923882.1 → XP_046779838.1  B-cell lymphoma 6 protein homolog isoform X1

    UniProtKB/TrEMBL
    A0A8V0YN89
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q5ZM39.1 GenPept UniProtKB/Swiss-Prot:Q5ZM39

Gene LinkOut

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