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DR1 down-regulator of transcription 1 [ Gallus gallus (chicken) ]

Gene ID: 424496, updated on 17-Aug-2024

Summary

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Symbol
DR1provided by CGNC
Full Name
down-regulator of transcription 1provided by CGNC
Primary source
CGNC:4374
See related
Ensembl:ENSGALG00010021701
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs
human mouse all
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Genomic context

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See DR1 in Genome Data Viewer
Location:
chromosome: 8
Exon count:
3
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 8 NC_052539.1 (13663906..13676412, complement)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 8 NC_052580.1 (13670576..13683087, complement)

Chromosome 8 - NC_052539.1Genomic Context describing neighboring genes Neighboring gene BCAR3 adaptor protein, NSP family member Neighboring gene uncharacterized LOC107053964 Neighboring gene formin binding protein 1 like Neighboring gene retinol dehydrogenase 8 like 2 Neighboring gene coiled-coil domain containing 18 Neighboring gene transmembrane p24 trafficking protein 5

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis. Caldwell RB, et al. Genome Biol, 2005. PMID 15642098, Free PMC Article
  2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
  3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  4. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables TBP-class protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables core promoter sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables general transcription initiation factor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein heterodimerization activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in RNA polymerase II preinitiation complex assembly IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in chromatin remodeling IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of negative cofactor 2 complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
protein Dr1
Names
NC2-beta
TATA-binding protein-associated phosphoprotein
down-regulator of transcription 1, TBP-binding (negative cofactor 2)
negative cofactor 2-beta

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001008478.2 → NP_001008478.1  protein Dr1

    See identical proteins and their annotated locations for NP_001008478.1

    Status: PROVISIONAL

    Source sequence(s)
    JAENSK010000239
    UniProtKB/Swiss-Prot
    Q5ZMV3
    Related
    ENSGALP00010031638.1, ENSGALT00010052731.1
    Conserved Domains (1) summary
    cl23735
    Location:7 → 130
    H4; Histone H4, one of the four histones, along with H2A, H2B and H3, which forms the eukaryotic nucleosome core; along with H3, it plays a central role in nucleosome formation; histones bind to DNA and wrap the genetic material into "beads on a string" in ...

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052539.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    13663906..13676412 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052580.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    13670576..13683087 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q5ZMV3.1 GenPept UniProtKB/Swiss-Prot:Q5ZMV3

Gene LinkOut

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