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MED25 Mediator complex subunit 25 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 42385, updated on 2-Nov-2024

Summary

Official Symbol
MED25provided by FlyBase
Official Full Name
Mediator complex subunit 25provided by FlyBase
Primary source
FLYBASE:FBgn0038760
Locus tag
Dmel_CG12254
See related
AllianceGenome:FB:FBgn0038760
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Arc92; CG12254; dARC92; dDrip97; Dmel\CG12254; LD07688; med25; Med25
Summary
Predicted to enable transcription coregulator activity. Involved in positive regulation of antibacterial peptide biosynthetic process. Predicted to be located in nucleoplasm. Predicted to be part of mediator complex and transcription regulator complex. Is expressed in organism. Orthologous to human MED25 (mediator complex subunit 25). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
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Genomic context

See MED25 in Genome Data Viewer
Location:
92C1-92C1; 3-67 cM
Exon count:
1
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (20008947..20011712)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (15834669..15837434)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene Heparan sulfate 6-O-sulfotransferase Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables transcription coregulator activity ISS
Inferred from Sequence or Structural Similarity
more info
 
Component Evidence Code Pubs
part_of mediator complex IBA
Inferred from Biological aspect of Ancestor
more info
 
part_of mediator complex ISS
Inferred from Sequence or Structural Similarity
more info
 
located_in nucleoplasm ISS
Inferred from Sequence or Structural Similarity
more info
PubMed 
part_of transcription regulator complex IBA
Inferred from Biological aspect of Ancestor
more info
 

General protein information

Preferred Names
mediator complex subunit 25
Names
CG12254-PA
MED25-PA

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    20008947..20011712
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_142597.4NP_650854.1  mediator complex subunit 25 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_650854.1

    Status: REVIEWED

    UniProtKB/Swiss-Prot
    Q9VDR1
    Related
    FBpp0083234
    Conserved Domains (2) summary
    pfam11232
    Location:524671
    Med25; Mediator complex subunit 25 PTOV activation and synapsin 2
    pfam11265
    Location:4218
    Med25_VWA; Mediator complex subunit 25 von Willebrand factor type A