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Hs6st - Heparan sulfate 6-O-sulfotransferase

Predicted to enable heparan sulfate 6-O-sulfotransferase activity. Involved in several processes, including chaeta development; heparan sulfate proteoglycan biosynthetic process; and imaginal disc-derived wing margin morphogenesis. Predicted to be integral component of membrane. Is expressed in several structures, including dorsal ectoderm; early extended germ band embryo; eye disc anterior to the morphogenetic furrow; larval tagma; and prothoracic gland. Human ortholog(s) of this gene implicated in Paganini-Miozzo syndrome and hypogonadotropic hypogonadism 15 with or without anosmia. Orthologous to several human genes including HS6ST1 (heparan sulfate 6-O-sulfotransferase 1) and HS6ST3 (heparan sulfate 6-O-sulfotransferase 3). [provided by Alliance of Genome Resources, Apr 2022]

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Species Gene Architecture aa