AMBRA1 autophagy and beclin 1 regulator 1 [Gallus gallus (chicken)] - Gene

Summary

Symbol: AMBRA1provided by CGNC
Full Name: autophagy and beclin 1 regulator 1provided by CGNC
Primary source: CGNC:51918
See related: Ensembl:ENSGALG00010023866
Gene type: protein coding
RefSeq status: MODEL
Organism: Gallus gallus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs: human mouse all
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Genomic context

Location:: chromosome: 5

Exon count:: 20

Annotation release	Status	Assembly	Chr	Location
106	current	bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2)	5	NC_052536.1 (23039895..23166054)
106	current	bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2)	5	NC_052577.1 (23007492..23133648)

Chromosome 5 - NC_052536.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

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General gene information

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Homology

NCBI Orthologs

Orthologs from OrthoDB

Gene Ontology Provided by RefSeq

Function	Evidence Code	Pubs
enables protein binding	IEA Inferred from Electronic Annotation more info	PubMed

Process	Evidence Code	Pubs
involved_in autophagy	IEA Inferred from Electronic Annotation more info	PubMed

Component	Evidence Code	Pubs
located_in intracellular membrane-bounded organelle	IEA Inferred from Electronic Annotation more info	PubMed

General protein information

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Preferred Names: activating molecule in BECN1-regulated autophagy protein 1

Names: activating molecule in beclin-1-regulated autophagy; autophagy/beclin-1 regulator 1; ischemia related factor NYW-1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

NC_052536.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Range

23039895..23166054

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GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_046942520.1 → XP_046798476.1 activating molecule in BECN1-regulated autophagy protein 1 isoform X1
XM_046942522.1 → XP_046798478.1 activating molecule in BECN1-regulated autophagy protein 1 isoform X2

UniProtKB/TrEMBL

A0A8V1A264
XM_004941601.5 → XP_004941658.1 activating molecule in BECN1-regulated autophagy protein 1 isoform X1

See identical proteins and their annotated locations for XP_004941658.1

UniProtKB/TrEMBL

A0A8V0ZPH4

Conserved Domains (2) summary

sd00039
Location:59 → 92

7WD40; WD40 repeat [structural motif]

cl25539
Location:59 → 198

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
XM_001233288.7 → XP_001233289.3 activating molecule in BECN1-regulated autophagy protein 1 isoform X2

UniProtKB/TrEMBL

A0A8V0ZPH4, A0A8V1A264

Related

ENSGALP00010035319.1, ENSGALT00010058160.1

Conserved Domains (2) summary

sd00039
Location:59 → 92

7WD40; WD40 repeat [structural motif]

cl29593
Location:59 → 198

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
XM_015287216.4 → XP_015142702.1 activating molecule in BECN1-regulated autophagy protein 1 isoform X3

Conserved Domains (4) summary

COG2319
Location:48 → 198

WD40; WD40 repeat [General function prediction only]

PTZ00233
Location:670 → 899

PTZ00233; variable surface protein Vir18; Provisional

sd00039
Location:59 → 92

7WD40; WD40 repeat [structural motif]

cl02567
Location:59 → 198

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
XM_015287217.4 → XP_015142703.1 activating molecule in BECN1-regulated autophagy protein 1 isoform X4

Conserved Domains (4) summary

COG2319
Location:48 → 198

WD40; WD40 repeat [General function prediction only]

PTZ00233
Location:669 → 898

PTZ00233; variable surface protein Vir18; Provisional

sd00039
Location:59 → 92

7WD40; WD40 repeat [structural motif]

cl02567
Location:59 → 198

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
XM_025151377.3 → XP_025007145.1 activating molecule in BECN1-regulated autophagy protein 1 isoform X1

UniProtKB/TrEMBL

A0A8V0ZPH4

Conserved Domains (2) summary

sd00039
Location:59 → 92

7WD40; WD40 repeat [structural motif]

cl25539
Location:59 → 198

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
XM_046942521.1 → XP_046798477.1 activating molecule in BECN1-regulated autophagy protein 1 isoform X1

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

NC_052577.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Range

23007492..23133648

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_046919523.1 → XP_046775479.1 activating molecule in BECN1-regulated autophagy protein 1 isoform X1
XM_040673672.2 → XP_040529606.1 activating molecule in BECN1-regulated autophagy protein 1 isoform X1

UniProtKB/TrEMBL

A0A8V0ZPH4

Conserved Domains (2) summary

sd00039
Location:59 → 92

7WD40; WD40 repeat [structural motif]

cl29593
Location:59 → 198

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
XM_040673674.2 → XP_040529608.1 activating molecule in BECN1-regulated autophagy protein 1 isoform X2

UniProtKB/TrEMBL

A0A8V0ZPH4

Conserved Domains (2) summary

sd00039
Location:59 → 92

7WD40; WD40 repeat [structural motif]

cl29593
Location:59 → 198

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
XM_040673676.2 → XP_040529610.1 activating molecule in BECN1-regulated autophagy protein 1 isoform X3

Conserved Domains (3) summary

PTZ00233
Location:670 → 899

PTZ00233; variable surface protein Vir18; Provisional

sd00039
Location:59 → 92

7WD40; WD40 repeat [structural motif]

cl29593
Location:59 → 198

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
XM_040673677.2 → XP_040529611.1 activating molecule in BECN1-regulated autophagy protein 1 isoform X4

Conserved Domains (3) summary

PTZ00233
Location:669 → 898

PTZ00233; variable surface protein Vir18; Provisional

sd00039
Location:59 → 92

7WD40; WD40 repeat [structural motif]

cl29593
Location:59 → 198

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
XM_040673673.2 → XP_040529607.1 activating molecule in BECN1-regulated autophagy protein 1 isoform X1

UniProtKB/TrEMBL

A0A8V0ZPH4

Conserved Domains (2) summary

sd00039
Location:59 → 92

7WD40; WD40 repeat [structural motif]

cl29593
Location:59 → 198

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
XM_040673675.1 → XP_040529609.1 activating molecule in BECN1-regulated autophagy protein 1 isoform X2

UniProtKB/TrEMBL

A0A8V0ZPH4

Conserved Domains (2) summary

sd00039
Location:59 → 92

7WD40; WD40 repeat [structural motif]

cl29593
Location:59 → 198

WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
XM_046919524.1 → XP_046775480.1 activating molecule in BECN1-regulated autophagy protein 1 isoform X1

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

NM_001012584.1: Suppressed sequence

Description

NM_001012584.1: This RefSeq was suppressed temporarily based on the calculation that the encoded protein was shorter than proteins from the putative ortholog from human: FLJ20294 (GeneID:55626).