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CG31224 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 42237, updated on 18-Sep-2024

Summary

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Official Symbol
CG31224provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0051224
Locus tag
Dmel_CG31224
See related
AllianceGenome:FB:FBgn0051224
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG17796; CG7696; Dmel\CG31224; l(3)c00083
Summary
Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in regulation of transcription by RNA polymerase II. Predicted to be located in nucleus. Is expressed in organism. Orthologous to human FIZ1 (FLT3 interacting zinc finger 1) and ZBTB44 (zinc finger and BTB domain containing 44). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
all
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Genomic context

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See CG31224 in Genome Data Viewer
Location:
91B8-91B8; 3-64 cM
Exon count:
6
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (18650121..18659309, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (14475843..14485031, complement)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene qin Neighboring gene transfer RNA:Proline-TGG 1-5 Neighboring gene uncharacterized protein Neighboring gene Cleavage stimulation factor 64 kD subunit Neighboring gene Cleavage and polyadenylation specificity factor 73 Neighboring gene Golgi SNARE, 28 kDa

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. A complementary transposon tool kit for Drosophila melanogaster using P and piggyBac. Thibault ST, et al. Nat Genet, 2004 Mar. PMID 14981521
  2. Homeostasis of glutamate neurotransmission is altered in Drosophila Inositol 1,4,5-trisphosphate receptor mutants. Nair S, et al. Invert Neurosci, 2007 Sep. PMID 17492321
  3. Specific transcriptional responses to juvenile hormone and ecdysone in Drosophila. Beckstead RB, et al. Insect Biochem Mol Biol, 2007 Jun. PMID 17517334, Free PMC Article
  4. A functional screen reveals an extensive layer of transcriptional and splicing control underlying RAS/MAPK signaling in Drosophila. Ashton-Beaucage D, et al. PLoS Biol, 2014 Mar. PMID 24643257, Free PMC Article
  5. Rapid and efficient cDNA library screening by self-ligation of inverse PCR products (SLIP). Hoskins RA, et al. Nucleic Acids Res, 2005 Dec 2. PMID 16326860, Free PMC Article

See all (28) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Markers

Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables DNA-binding transcription repressor activity, RNA polymerase II-specific ISS
Inferred from Sequence or Structural Similarity
more info
  
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding ISS
Inferred from Sequence or Structural Similarity
more info
  
Process Evidence Code Pubs
involved_in regulation of transcription by RNA polymerase II ISS
Inferred from Sequence or Structural Similarity
more info
  
Component Evidence Code Pubs
located_in nucleus ISS
Inferred from Sequence or Structural Similarity
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG31224-PA
CG31224-PB
CG31224-PC
lethal (3) c00083

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    18650121..18659309 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001300467.1 → NP_001287396.1  uncharacterized protein Dmel_CG31224, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001287396.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VE54
    Conserved Domains (5) summary
    PHA00733
    Location:1527 → 1623
    PHA00733; hypothetical protein
    COG5048
    Location:1637 → 1780
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:1698 → 1718
    ZF_C2H2; C2H2 Zn finger [structural motif]
    sd00019
    Location:1554 → 1573
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:1506 → 1531
    zf-H2C2_2; Zinc-finger double domain

  2. NM_169826.2 → NP_732361.1  uncharacterized protein Dmel_CG31224, isoform A [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_732361.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VE54
    Related
    FBpp0083106
    Conserved Domains (5) summary
    PHA00733
    Location:1527 → 1623
    PHA00733; hypothetical protein
    COG5048
    Location:1637 → 1780
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:1698 → 1718
    ZF_C2H2; C2H2 Zn finger [structural motif]
    sd00019
    Location:1554 → 1573
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:1506 → 1531
    zf-H2C2_2; Zinc-finger double domain

  3. NM_001300468.1 → NP_001287397.1  uncharacterized protein Dmel_CG31224, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001287397.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VE54
    Conserved Domains (5) summary
    PHA00733
    Location:1527 → 1623
    PHA00733; hypothetical protein
    COG5048
    Location:1637 → 1780
    COG5048; FOG: Zn-finger [General function prediction only]
    sd00017
    Location:1698 → 1718
    ZF_C2H2; C2H2 Zn finger [structural motif]
    sd00019
    Location:1554 → 1573
    ZF_C2H2; C2H2 Zn finger [structural motif]
    pfam13465
    Location:1506 → 1531
    zf-H2C2_2; Zinc-finger double domain
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q86NX5 Q86NX5
Q8IG87 Q8IG87
Q8T3J8 Q8T3J8
Q9VE54 Q9VE54

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