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CASP8AP2 caspase 8 associated protein 2 [ Gallus gallus (chicken) ]

Gene ID: 421810, updated on 17-Aug-2024

Summary

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Symbol
CASP8AP2provided by CGNC
Full Name
caspase 8 associated protein 2provided by CGNC
Primary source
CGNC:11637
See related
Ensembl:ENSGALG00010003300
Gene type
protein coding
RefSeq status
MODEL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs
human mouse all
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Genomic context

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See CASP8AP2 in Genome Data Viewer
Location:
chromosome: 3
Exon count:
12
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 3 NC_052534.1 (75111640..75133965, complement)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 3 NC_052575.1 (74909329..74931617, complement)

Chromosome 3 - NC_052534.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC121110251 Neighboring gene BTB domain and CNC homolog 2 Neighboring gene gap junction protein, alpha 10, 62kDa Neighboring gene midasin AAA ATPase 1 Neighboring gene ankyrin repeat domain 6 Neighboring gene LYR motif containing 2 Neighboring gene microRNA 1686

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Markers

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables transcription corepressor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in Fas signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in activation of cysteine-type endopeptidase activity involved in apoptotic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in extrinsic apoptotic signaling pathway via death domain receptors IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in PML body IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
CASP8-associated protein 2
Names
CASP8 associated protein 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052534.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    75111640..75133965 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040697838.2 → XP_040553772.1  CASP8-associated protein 2 isoform X1

    UniProtKB/TrEMBL
    A0A8V0X974, A0A8V0XIV3
    Conserved Domains (2) summary
    cd12202
    Location:1953 → 2017
    CASP8AP2; Caspase 8-associated protein 2 myb-like domain
    COG1196
    Location:66 → 144
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

  2. XM_040697839.2 → XP_040553773.1  CASP8-associated protein 2 isoform X2

    UniProtKB/TrEMBL
    A0A8V0X974, A0A8V0XIU9
    Related
    ENSGALP00010004650.1, ENSGALT00010007736.1
    Conserved Domains (1) summary
    COG1196
    Location:66 → 144
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

  3. XM_419834.7 → XP_419834.3  CASP8-associated protein 2 isoform X1

    UniProtKB/TrEMBL
    A0A8V0X974, A0A8V0XIV3
    Related
    ENSGALP00010004655.1, ENSGALT00010007742.1
    Conserved Domains (2) summary
    cd12202
    Location:1953 → 2017
    CASP8AP2; Caspase 8-associated protein 2 myb-like domain
    COG1196
    Location:66 → 144
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

  4. XM_025149055.3 → XP_025004823.2  CASP8-associated protein 2 isoform X1

    UniProtKB/TrEMBL
    A0A8V0X974, A0A8V0XIV3
    Conserved Domains (2) summary
    cd12202
    Location:1953 → 2017
    CASP8AP2; Caspase 8-associated protein 2 myb-like domain
    COG1196
    Location:66 → 144
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

RNA

  1. XR_001466088.4 RNA Sequence

    Related
    ENSGALT00010007739.1

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052575.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    74909329..74931617 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040667147.2 → XP_040523081.1  CASP8-associated protein 2 isoform X1

    UniProtKB/TrEMBL
    A0A8V0X974
    Conserved Domains (2) summary
    cd12202
    Location:1953 → 2017
    CASP8AP2; Caspase 8-associated protein 2 myb-like domain
    COG1196
    Location:66 → 144
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

  2. XM_040667148.2 → XP_040523082.1  CASP8-associated protein 2 isoform X2

    UniProtKB/TrEMBL
    A0A8V0X974
    Conserved Domains (1) summary
    COG1196
    Location:66 → 144
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

  3. XM_040667145.2 → XP_040523079.1  CASP8-associated protein 2 isoform X1

    UniProtKB/TrEMBL
    A0A8V0X974
    Conserved Domains (2) summary
    cd12202
    Location:1953 → 2017
    CASP8AP2; Caspase 8-associated protein 2 myb-like domain
    COG1196
    Location:66 → 144
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

  4. XM_040667146.2 → XP_040523080.1  CASP8-associated protein 2 isoform X1

    UniProtKB/TrEMBL
    A0A8V0X974
    Conserved Domains (2) summary
    cd12202
    Location:1953 → 2017
    CASP8AP2; Caspase 8-associated protein 2 myb-like domain
    COG1196
    Location:66 → 144
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]

RNA

  1. XR_005848152.2 RNA Sequence

Nucleotide Protein Strain
Heading Accession and Version

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