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cysu Curly Su [ Drosophila melanogaster (fruit fly) ]

Gene ID: 42100, updated on 2-Nov-2024

Summary

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Official Symbol
cysuprovided by FlyBase
Official Full Name
Curly Suprovided by FlyBase
Primary source
FLYBASE:FBgn0038511
Locus tag
Dmel_CG5873
See related
AllianceGenome:FB:FBgn0038511
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG5873; Cysu; Dmel\CG5873; HPX5
Summary
Predicted to enable peroxidase activity. Predicted to be involved in response to oxidative stress. Is expressed in several structures, including adult head; embryonic anal pad; embryonic dorsal epidermis; embryonic/larval tracheal section; and gut section. [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
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Genomic context

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See cysu in Genome Data Viewer
Location:
90A6-90B1; 3-60 cM
Exon count:
10
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (17425768..17446499)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (13251490..13272221)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene long non-coding RNA:CR46052 Neighboring gene long non-coding RNA:CR46053 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Eclosion hormone Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The essential requirement of an animal heme peroxidase protein during the wing maturation process in Drosophila. Bailey D, et al. BMC Dev Biol, 2017 Jan 11. PMID 28077066, Free PMC Article
  2. Genetic analysis of Eclosion hormone action during Drosophila larval ecdysis. Krüger E, et al. Development, 2015 Dec 15. PMID 26395475
  3. Curly Encodes Dual Oxidase, Which Acts with Heme Peroxidase Curly Su to Shape the Adult Drosophila Wing. Hurd TR, et al. PLoS Genet, 2015 Nov. PMID 26587980, Free PMC Article
  4. Metabolic and transcriptional response to a high-fat diet in Drosophila melanogaster. Heinrichsen ET, et al. Mol Metab, 2014 Feb. PMID 24567903, Free PMC Article
  5. Septin 4, the drosophila ortholog of human CDCrel-1, accumulates in parkin mutant brains and is functionally related to the Nedd4 E3 ubiquitin ligase. Muñoz-Soriano V, et al. J Mol Neurosci, 2012 Sep. PMID 22562816

See all (42) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

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Products Interactant Other Gene Complex Source Pubs Description

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables heme binding IEA
Inferred from Electronic Annotation
more info
  
enables peroxidase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables peroxidase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in response to oxidative stress IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
curly Su
Names
CG5873-PA
cysu-PA
NP_650627.1

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    17425768..17446499
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_142370.2 → NP_650627.1  curly Su [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_650627.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VEJ9
    Related
    FBpp0082883
    Conserved Domains (2) summary
    cd09823
    Location:305 → 687
    peroxinectin_like; peroxinectin_like animal heme peroxidases
    pfam03098
    Location:155 → 692
    An_peroxidase; Animal haem peroxidase
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q8MT50 Q8MT50
Q9VEJ9 Q9VEJ9

Gene LinkOut

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