U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

CG5860 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 42095, updated on 2-Nov-2024

Summary

Go to the top of the page Help
Official Symbol
CG5860provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0038506
Locus tag
Dmel_CG5860
See related
AllianceGenome:FB:FBgn0038506
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
Dmel\CG5860; FBgn0038506
Summary
Predicted to enable aspartic-type endopeptidase activity. Predicted to be involved in apoptotic process and proteolysis. Predicted to be active in lysosome. Human ortholog(s) of this gene implicated in essential hypertension; familial juvenile hyperuricemic nephropathy; hand, foot and mouth disease; hypertension; and portal hypertension. Orthologous to human REN (renin). [provided by Alliance of Genome Resources, Nov 2024]
Orthologs
all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See CG5860 in Genome Data Viewer
Location:
90A6-90A6; 3-60 cM
Exon count:
1
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (17409619..17410840)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (13235341..13236562)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Assessment of genome-wide protein function classification for Drosophila melanogaster. Mi H, et al. Genome Res, 2003 Sep. PMID 12952880, Free PMC Article
  2. Single-cell transcriptome characteristics of testicular terminal epithelium lineages during aging in the Drosophila. Chen X, et al. Aging Cell, 2024 Mar. PMID 38044573, Free PMC Article
  3. A Drosophila protein-interaction map centered on cell-cycle regulators. Stanyon CA, et al. Genome Biol, 2004. PMID 15575970, Free PMC Article
  4. Cold acclimation wholly reorganizes the Drosophila melanogaster transcriptome and metabolome. MacMillan HA, et al. Sci Rep, 2016 Jun 30. PMID 27357258, Free PMC Article
  5. Transient junction anisotropies orient annular cell polarization in the Drosophila airway tubes. Hosono C, et al. Nat Cell Biol, 2015 Dec. PMID 26551273

See all (22) citations in PubMed

GeneRIFs: Gene References Into Functions

Interactions

Go to the top of the page Help
Products Interactant Other Gene Complex Source Pubs Description

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables aspartic-type endopeptidase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables aspartic-type endopeptidase activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in apoptotic process IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in proteolysis IBA
Inferred from Biological aspect of Ancestor
more info
  
involved_in proteolysis IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
is_active_in lysosome IBA
Inferred from Biological aspect of Ancestor
more info
  

General protein information

Go to the top of the page Help
Preferred Names
uncharacterized protein
Names
CG5860-PA
NP_650622.1

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    17409619..17410840
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_142365.2 → NP_650622.1  uncharacterized protein Dmel_CG5860 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_650622.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q9VEK4
    Related
    FBpp0082879
    Conserved Domains (2) summary
    pfam00026
    Location:63 → 369
    Asp; Eukaryotic aspartyl protease
    cl11403
    Location:61 → 368
    pepsin_retropepsin_like; Cellular and retroviral pepsin-like aspartate proteases
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9VEK4 Q9VEK4

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Other Literature Sources
Molecular Biology Databases
Research Materials
Tools
Miscellaneous