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LOC420419 mitogen-activated protein kinase kinase kinase 3-like [ Gallus gallus (chicken) ]

Gene ID: 420419, updated on 17-Aug-2024

Summary

Symbol
LOC420419provided by CGNC
Full Name
mitogen-activated protein kinase kinase kinase 3-likeprovided by CGNC
Primary source
CGNC:51255
See related
Ensembl:ENSGALG00010026516
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Also known as
MAPKKK3L
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Genomic context

See LOC420419 in Genome Data Viewer
Location:
chromosome: 2
Exon count:
19
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 2 NC_052533.1 (4733026..4801287, complement)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 2 NC_052574.1 (4735504..4803796, complement)

Chromosome 2 - NC_052533.1Genomic Context describing neighboring genes Neighboring gene U6 spliceosomal RNA Neighboring gene deleted in lung and esophageal cancer 1 Neighboring gene acetyl-CoA acyltransferase 1 Neighboring gene uncharacterized LOC121112363 Neighboring gene myeloid differentiation primary response 88

Genomic regions, transcripts, and products

General gene information

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables protein kinase activity IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
mitogen-activated protein kinase kinase kinase 3-like

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001079726.2NP_001073194.1  mitogen-activated protein kinase kinase kinase 3-like

    See identical proteins and their annotated locations for NP_001073194.1

    Status: PROVISIONAL

    Source sequence(s)
    JAENSK010000035
    UniProtKB/TrEMBL
    A0A8V1A8I7, F1NAY6, Q5ZLW4
    Related
    ENSGALP00010039540.1, ENSGALT00010064459.1
    Conserved Domains (3) summary
    cd06405
    Location:42120
    PB1_Mekk2_3; The PB1 domain is present in the two mitogen-activated protein kinase kinases MEKK2 and MEKK3 which are two members of the signaling kinase cascade involved in angiogenesis and early cardiovascular development. The PB1 domain of MEKK2 (and/or MEKK3) ...
    smart00220
    Location:357617
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cd06653
    Location:354617
    STKc_MEKK3_like_u1; Catalytic domain of an Uncharacterized subfamily of Mitogen-Activated Protein (MAP)/Extracellular signal-Regulated Kinase (ERK) Kinase Kinase 3-like Serine/Threonine Kinases

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052533.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    4733026..4801287 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015281099.4XP_015136585.1  mitogen-activated protein kinase kinase kinase 3-like isoform X2

    UniProtKB/TrEMBL
    A0A8V1A8I7
    Conserved Domains (3) summary
    cd06405
    Location:41119
    PB1_Mekk2_3; The PB1 domain is present in the two mitogen-activated protein kinase kinases MEKK2 and MEKK3 which are two members of the signaling kinase cascade involved in angiogenesis and early cardiovascular development. The PB1 domain of MEKK2 (and/or MEKK3) ...
    smart00220
    Location:356616
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cd06653
    Location:353616
    STKc_MEKK3_like_u1; Catalytic domain of an Uncharacterized subfamily of Mitogen-Activated Protein (MAP)/Extracellular signal-Regulated Kinase (ERK) Kinase Kinase 3-like Serine/Threonine Kinases
  2. XM_046921373.1XP_046777329.1  mitogen-activated protein kinase kinase kinase 3-like isoform X4

    UniProtKB/TrEMBL
    A0A8V1A8I7
  3. XM_046921371.1XP_046777327.1  mitogen-activated protein kinase kinase kinase 3-like isoform X3

    UniProtKB/TrEMBL
    A0A8V1A8I3, A0A8V1A8I7
    Related
    ENSGALP00010039536.1, ENSGALT00010064451.1
  4. XM_046921353.1XP_046777309.1  mitogen-activated protein kinase kinase kinase 3-like isoform X1

    UniProtKB/TrEMBL
    A0A8V1A8I7, F1NAY6, Q5ZLW4
  5. XM_046921362.1XP_046777318.1  mitogen-activated protein kinase kinase kinase 3-like isoform X1

    UniProtKB/TrEMBL
    A0A8V1A8I7, F1NAY6, Q5ZLW4
  6. XM_015281097.4XP_015136583.1  mitogen-activated protein kinase kinase kinase 3-like isoform X1

    UniProtKB/TrEMBL
    A0A8V1A8I7, F1NAY6, Q5ZLW4
    Conserved Domains (3) summary
    cd06405
    Location:42120
    PB1_Mekk2_3; The PB1 domain is present in the two mitogen-activated protein kinase kinases MEKK2 and MEKK3 which are two members of the signaling kinase cascade involved in angiogenesis and early cardiovascular development. The PB1 domain of MEKK2 (and/or MEKK3) ...
    smart00220
    Location:357617
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cd06653
    Location:354617
    STKc_MEKK3_like_u1; Catalytic domain of an Uncharacterized subfamily of Mitogen-Activated Protein (MAP)/Extracellular signal-Regulated Kinase (ERK) Kinase Kinase 3-like Serine/Threonine Kinases

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052574.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    4735504..4803796 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046910875.1XP_046766831.1  mitogen-activated protein kinase kinase kinase 3-like isoform X2

    UniProtKB/TrEMBL
    A0A8V1A8I7
  2. XM_046910877.1XP_046766833.1  mitogen-activated protein kinase kinase kinase 3-like isoform X4

    UniProtKB/TrEMBL
    A0A8V1A8I7
  3. XM_046910876.1XP_046766832.1  mitogen-activated protein kinase kinase kinase 3-like isoform X3

    UniProtKB/TrEMBL
    A0A8V1A8I3, A0A8V1A8I7
  4. XM_046910873.1XP_046766829.1  mitogen-activated protein kinase kinase kinase 3-like isoform X1

    UniProtKB/TrEMBL
    A0A8V1A8I7, F1NAY6, Q5ZLW4
  5. XM_046910874.1XP_046766830.1  mitogen-activated protein kinase kinase kinase 3-like isoform X1

    UniProtKB/TrEMBL
    A0A8V1A8I7, F1NAY6, Q5ZLW4
  6. XM_046910872.1XP_046766828.1  mitogen-activated protein kinase kinase kinase 3-like isoform X1

    UniProtKB/TrEMBL
    A0A8V1A8I7, F1NAY6, Q5ZLW4

RNA

  1. XR_006933396.1 RNA Sequence