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CDON cell adhesion associated, oncogene regulated [ Gallus gallus (chicken) ]

Gene ID: 419710, updated on 6-Jun-2024

Summary

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Symbol
CDONprovided by CGNC
Full Name
cell adhesion associated, oncogene regulatedprovided by CGNC
Primary source
CGNC:51066
See related
Ensembl:ENSGALG00010023809
Gene type
protein coding
RefSeq status
MODEL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs
human mouse all
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Genomic context

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See CDON in Genome Data Viewer
Location:
chromosome: 24
Exon count:
19
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 24 NC_052555.1 (379852..420398, complement)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 24 NC_052596.1 (339651..380671, complement)

Chromosome 24 - NC_052555.1Genomic Context describing neighboring genes Neighboring gene HYLS1, centriolar and ciliogenesis associated Neighboring gene hemicentin-2-like Neighboring gene pseudouridylate synthase 3 Neighboring gene checkpoint kinase 1 Neighboring gene STT3A, catalytic subunit of the oligosaccharyltransferase complex

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Sonic Hedgehog promotes the survival of neural crest cells by limiting apoptosis induced by the dependence receptor CDON during branchial arch development. Delloye-Bourgeois C, et al. Biochem Biophys Res Commun, 2014 Sep 26. PMID 25193697
  2. Cdon acts as a Hedgehog decoy receptor during proximal-distal patterning of the optic vesicle. Cardozo MJ, et al. Nat Commun, 2014 Jul 8. PMID 25001599, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. In the developing optic vesicle, Cdon predominantly localizes to the basolateral side of neuroepithelial cells, promotes the enlargement of the neuroepithelial basal end-foot and traps Hedgehog protein, thereby limiting its dispersion.
    Title: Cdon acts as a Hedgehog decoy receptor during proximal-distal patterning of the optic vesicle.
  2. SHH promotes the survival of neural crest cells by limiting apoptosis induced by the dependence receptor CDON during branchial arch development.
    Title: Sonic Hedgehog promotes the survival of neural crest cells by limiting apoptosis induced by the dependence receptor CDON during branchial arch development.
Submit: New GeneRIF Correction

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in axon guidance IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell-cell adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in nervous system development IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in axon IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
cell adhesion molecule-related/down-regulated by oncogenes; LOW QUALITY PROTEIN: cell adhesion molecule-related/down-regulated by oncogenes
Names
Cdon homolog
surface glycoprotein, Ig superfamily member

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052555.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    379852..420398 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046903791.1 → XP_046759747.1  LOW QUALITY PROTEIN: cell adhesion molecule-related/down-regulated by oncogenes

    UniProtKB/TrEMBL
    A0A8V0ZUE7
    Related
    ENSGALP00010035213.1, ENSGALT00010058035.1

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052596.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    339651..380671 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040690429.2 → XP_040546363.1  cell adhesion molecule-related/down-regulated by oncogenes

    UniProtKB/TrEMBL
    A0A8V0ZUE7
    Conserved Domains (4) summary
    smart00408
    Location:320 → 381
    IGc2; Immunoglobulin C-2 Type
    smart00409
    Location:127 → 193
    IG; Immunoglobulin
    cd00063
    Location:591 → 678
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd00096
    Location:314 → 318
    Ig; Ig strand A' [structural motif]

  2. XM_040690428.2 → XP_040546362.1  cell adhesion molecule-related/down-regulated by oncogenes

    UniProtKB/TrEMBL
    A0A8V0ZUE7
    Conserved Domains (4) summary
    smart00408
    Location:320 → 381
    IGc2; Immunoglobulin C-2 Type
    smart00409
    Location:127 → 193
    IG; Immunoglobulin
    cd00063
    Location:591 → 678
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd00096
    Location:314 → 318
    Ig; Ig strand A' [structural motif]

  3. XM_040690427.2 → XP_040546361.1  cell adhesion molecule-related/down-regulated by oncogenes

    UniProtKB/TrEMBL
    A0A8V0ZUE7
    Conserved Domains (4) summary
    smart00408
    Location:320 → 381
    IGc2; Immunoglobulin C-2 Type
    smart00409
    Location:127 → 193
    IG; Immunoglobulin
    cd00063
    Location:591 → 678
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd00096
    Location:314 → 318
    Ig; Ig strand A' [structural motif]

  4. XM_046932419.1 → XP_046788375.1  cell adhesion molecule-related/down-regulated by oncogenes

    UniProtKB/TrEMBL
    A0A8V0ZUE7
Nucleotide Protein Strain
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