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CG6006 uncharacterized protein [ Drosophila melanogaster (fruit fly) ]

Gene ID: 41962, updated on 18-Sep-2024

Summary

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Official Symbol
CG6006provided by FlyBase
Official Full Name
uncharacterized proteinprovided by FlyBase
Primary source
FLYBASE:FBgn0063649
Locus tag
Dmel_CG6006
See related
AllianceGenome:FB:FBgn0063649
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
BcDNA:SD04753; Dmel\CG6006
Summary
Predicted to enable transmembrane transporter activity. Predicted to be involved in transmembrane transport. Predicted to be integral component of membrane. Is expressed in adult head. Orthologous to human SLC22A23 (solute carrier family 22 member 23). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
all
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Genomic context

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See CG6006 in Genome Data Viewer
Location:
89B6-89B6; 3-58 cM
Exon count:
9
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (16154982..16171766)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (11980704..11997488)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene Stubble Neighboring gene MICOS subunit 26/27 Neighboring gene uncharacterized protein Neighboring gene 48 related 2 Neighboring gene antisense RNA:CR43472 Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Bicoid interacting protein 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. SLC22 Transporters in the Fly Renal System Regulate Response to Oxidative Stress In Vivo. Zhang P, et al. Int J Mol Sci, 2021 Dec 14. PMID 34948211, Free PMC Article
  2. Novel slc22 transporter homologs in fly, worm, and human clarify the phylogeny of organic anion and cation transporters. Eraly SA, et al. Physiol Genomics, 2004 Jun 17. PMID 15054140
  3. Brain Proteome of Drosophila melanogaster Is Enriched with Nuclear Proteins. Kuznetsova KG, et al. Biochemistry (Mosc), 2019 Jan. PMID 30927528
  4. Drosophila SLC22 Orthologs Related to OATs, OCTs, and OCTNs Regulate Development and Responsiveness to Oxidative Stress. Engelhart DC, et al. Int J Mol Sci, 2020 Mar 15. PMID 32183456, Free PMC Article
  5. Glial Glycolysis Is Essential for Neuronal Survival in Drosophila. Volkenhoff A, et al. Cell Metab, 2015 Sep 1. PMID 26235423

See all (31) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
uncharacterized protein
Names
CG6006-PB
CG6006-PC
CG6006-PD
CG6006-PE
CG6006-PF

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    16154982..16171766
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001104342.4 → NP_001097812.1  uncharacterized protein Dmel_CG6006, isoform C [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001097812.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    A2RVG5, Q8MQI2
    Conserved Domains (2) summary
    cd06174
    Location:222 → 579
    MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
    TIGR00898
    Location:90 → 581
    2A0119; cation transport protein

  2. NM_001260204.1 → NP_001247133.1  uncharacterized protein Dmel_CG6006, isoform E [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001247133.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8MQI2, Q9VEY2
    Conserved Domains (2) summary
    cd06174
    Location:183 → 545
    MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
    TIGR00898
    Location:51 → 547
    2A0119; cation transport protein

  3. NM_001260203.1 → NP_001247132.1  uncharacterized protein Dmel_CG6006, isoform D [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001247132.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8MQI2, Q9VEY2
    Conserved Domains (2) summary
    cd06174
    Location:183 → 545
    MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
    TIGR00898
    Location:51 → 547
    2A0119; cation transport protein

  4. NM_142268.2 → NP_650525.1  uncharacterized protein Dmel_CG6006, isoform B [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_650525.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8MQI2, Q9VEY2
    Related
    FBpp0082706
    Conserved Domains (2) summary
    cd06174
    Location:183 → 545
    MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
    TIGR00898
    Location:51 → 547
    2A0119; cation transport protein

  5. NM_001260205.1 → NP_001247134.1  uncharacterized protein Dmel_CG6006, isoform F [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_001247134.1

    Status: REVIEWED

    UniProtKB/TrEMBL
    Q8MQI2, Q9VEY2
    Conserved Domains (2) summary
    cd06174
    Location:183 → 545
    MFS; The Major Facilitator Superfamily (MFS) is a large and diverse group of secondary transporters that includes uniporters, symporters, and antiporters. MFS proteins facilitate the transport across cytoplasmic or internal membranes of a variety of ...
    TIGR00898
    Location:51 → 547
    2A0119; cation transport protein
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
A2RVG5 A2RVG5
Q8MQI2 Q8MQI2
Q9VEY2 Q9VEY2

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