U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

CLDN10 claudin 10 [ Gallus gallus (chicken) ]

Gene ID: 418790, updated on 17-Aug-2024

Summary

Go to the top of the page Help
Official Symbol
CLDN10provided by CGNC
Official Full Name
claudin 10provided by CGNC
Primary source
CGNC:13756
See related
Ensembl:ENSGALG00010005387
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Also known as
claudin-10
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
See CLDN10 in Genome Data Viewer
Location:
chromosome: 1
Exon count:
7
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 1 NC_052532.1 (146027758..146097958, complement)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 1 NC_052573.1 (146019402..146089756, complement)

Chromosome 1 - NC_052532.1Genomic Context describing neighboring genes Neighboring gene UDP-glucose glycoprotein glucosyltransferase 2 Neighboring gene DnaJ heat shock protein family (Hsp40) member C3 Neighboring gene uncharacterized LOC121107106 Neighboring gene DAZ interacting zinc finger protein 1 Neighboring gene ATP binding cassette subfamily C member 4 Neighboring gene uncharacterized LOC112531539 Neighboring gene uncharacterized LOC121108178

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

Related articles in PubMed

  1. Claudin-10 is required for relay of left-right patterning cues from Hensen's node to the lateral plate mesoderm. Collins MM, et al. Dev Biol, 2015 May 15. PMID 25744724
  2. Claudin 10 is a glandular epithelial marker in the chicken model as human epithelial ovarian cancer. Seo HW, et al. Int J Gynecol Cancer, 2010 Dec. PMID 21370593
  3. Chicken genomics resource: sequencing and annotation of 35,407 ESTs from single and multiple tissue cDNA libraries and CAP3 assembly of a chicken gene index. Carre W, et al. Physiol Genomics, 2006 May 16. PMID 16554550
  4. A comprehensive collection of chicken cDNAs. Boardman PE, et al. Curr Biol, 2002 Nov 19. PMID 12445392
  5. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

See all (6) citations in PubMed

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. The data demonstrate a novel role for Claudin-10 during the transmission of laterality information from Hensen's node to both the left and right sides of the embryo. [claudin-10]
    Title: Claudin-10 is required for relay of left-right patterning cues from Hensen's node to the lateral plate mesoderm.
  2. New insight into using the chicken as a suitable animal model for investigating the effect and function of CLDN in human ovarian cancer.
    Title: Claudin 10 is a glandular epithelial marker in the chicken model as human epithelial ovarian cancer.
Submit: New GeneRIF Correction

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables structural molecule activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in bicellular tight junction assembly IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in bicellular tight junction IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
claudin-10

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001277767.2 → NP_001264696.1  claudin-10 isoform 1 precursor

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).
    Source sequence(s)
    JAENSK010000025
    UniProtKB/TrEMBL
    A0A8V0XTM4, E1C926
    Related
    ENSGALP00010007373.1, ENSGALT00010012810.1
    Conserved Domains (1) summary
    cl21598
    Location:7 → 179
    PMP22_Claudin; PMP-22/EMP/MP20/Claudin family

  2. NM_001277768.1 → NP_001264697.1  claudin-10 isoform 2 precursor

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) uses an alternate in-frame splice junction at the 5' end of an internal exon compared to variant 1. The resulting isoform (2) has the same N- and C-termini but is shorter compared to isoform 1.
    Source sequence(s)
    BU121320, BU380770, BX930125, JAENSK010000025
    UniProtKB/TrEMBL
    A0A8V0XTM4
    Conserved Domains (1) summary
    cl21598
    Location:7 → 139
    PMP22_Claudin; PMP-22/EMP/MP20/Claudin family

  3. NM_001277769.2 → NP_001264698.1  claudin-10 isoform 3

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) has an alternate first exon in place of the first exon of variant 1. The resulting isoform (3) has a shorter and distinct N-terminus compared to isoform 1.
    Source sequence(s)
    BX936162, CV038199
    UniProtKB/TrEMBL
    A0A1D5NU32
    Conserved Domains (1) summary
    cl21598
    Location:20 → 129
    PMP22_Claudin; PMP-22/EMP/MP20/Claudin family

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052532.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    146027758..146097958 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046941332.1 → XP_046797288.1  claudin-10 isoform X1

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052573.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    146019402..146089756 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046908153.1 → XP_046764109.1  claudin-10 isoform X1

Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Molecular Biology Databases
Research Materials