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PI4KA phosphatidylinositol 4-kinase alpha [ Gallus gallus (chicken) ]

Gene ID: 416767, updated on 17-Aug-2024

Summary

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Symbol
PI4KAprovided by CGNC
Full Name
phosphatidylinositol 4-kinase alphaprovided by CGNC
Primary source
CGNC:50340
See related
Ensembl:ENSGALG00010024198
Gene type
protein coding
RefSeq status
MODEL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Also known as
PIK4CA
Orthologs
human mouse all
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Genomic context

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See PI4KA in Genome Data Viewer
Location:
chromosome: 15
Exon count:
56
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 15 NC_052546.1 (113421..170020)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 15 NC_052587.1 (118996..175589)

Chromosome 15 - NC_052546.1Genomic Context describing neighboring genes Neighboring gene clathrin, heavy chain-like 1 Neighboring gene synaptosome associated protein 29 Neighboring gene serpin family D member 1 Neighboring gene uncharacterized LOC107051622 Neighboring gene hypermethylated in cancer 2 Neighboring gene ubiquitin conjugating enzyme E2 L3

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 1-phosphatidylinositol 4-kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in phosphatidylinositol phosphate biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in phosphatidylinositol-mediated signaling IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
phosphatidylinositol 4-kinase alpha
Names
phosphatidylinositol 4-kinase, catalytic, alpha polypeptide
XP_004945537.2
XP_040540156.1
XP_040540157.1
XP_046757150.1
XP_046784257.1
XP_415062.4

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052546.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    113421..170020
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046901194.1 → XP_046757150.1  phosphatidylinositol 4-kinase alpha isoform X3

    UniProtKB/TrEMBL
    A0A8V0ZYM5
    Related
    ENSGALP00010036014.1, ENSGALT00010059050.1

  2. XM_004945480.5 → XP_004945537.2  phosphatidylinositol 4-kinase alpha isoform X1

    UniProtKB/TrEMBL
    A0A8V0ZYM1
    Related
    ENSGALP00010036009.1, ENSGALT00010059045.1
    Conserved Domains (2) summary
    cd00871
    Location:1568 → 1743
    PI4Ka; Phosphoinositide 4-kinase(PI4K), accessory domain (PIK domain); PIK domain is conserved in PI3 and PI4-kinases. Its role is unclear but it has been suggested to be involved in substrate presentation. PI4K phosphorylates hydroxylgroup at position 4 on the ...
    cd05167
    Location:1804 → 2122
    PI4Kc_III_alpha; Catalytic domain of Type III Phosphoinositide 4-kinase alpha

  3. XM_415062.8 → XP_415062.4  phosphatidylinositol 4-kinase alpha isoform X2

    Conserved Domains (2) summary
    cd00871
    Location:1567 → 1742
    PI4Ka; Phosphoinositide 4-kinase(PI4K), accessory domain (PIK domain); PIK domain is conserved in PI3 and PI4-kinases. Its role is unclear but it has been suggested to be involved in substrate presentation. PI4K phosphorylates hydroxylgroup at position 4 on the ...
    cd05167
    Location:1803 → 2121
    PI4Kc_III_alpha; Catalytic domain of Type III Phosphoinositide 4-kinase alpha

RNA

  1. XR_005840101.2 RNA Sequence

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052587.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    118996..175589
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046928301.1 → XP_046784257.1  phosphatidylinositol 4-kinase alpha isoform X3

  2. XM_040684222.2 → XP_040540156.1  phosphatidylinositol 4-kinase alpha isoform X1

    Conserved Domains (2) summary
    cd00871
    Location:1568 → 1743
    PI4Ka; Phosphoinositide 4-kinase(PI4K), accessory domain (PIK domain); PIK domain is conserved in PI3 and PI4-kinases. Its role is unclear but it has been suggested to be involved in substrate presentation. PI4K phosphorylates hydroxylgroup at position 4 on the ...
    cd05167
    Location:1804 → 2122
    PI4Kc_III_alpha; Catalytic domain of Type III Phosphoinositide 4-kinase alpha

  3. XM_040684223.2 → XP_040540157.1  phosphatidylinositol 4-kinase alpha isoform X2

    Conserved Domains (2) summary
    cd00871
    Location:1567 → 1742
    PI4Ka; Phosphoinositide 4-kinase(PI4K), accessory domain (PIK domain); PIK domain is conserved in PI3 and PI4-kinases. Its role is unclear but it has been suggested to be involved in substrate presentation. PI4K phosphorylates hydroxylgroup at position 4 on the ...
    cd05167
    Location:1803 → 2121
    PI4Kc_III_alpha; Catalytic domain of Type III Phosphoinositide 4-kinase alpha

RNA

  1. XR_005854327.2 RNA Sequence

Nucleotide Protein
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