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CtBP - C-terminal Binding Protein

Enables DNA-binding transcription factor binding activity; protein homodimerization activity; and transcription coregulator activity. Involved in several processes, including regulation of canonical Wnt signaling pathway; regulation of transcription by RNA polymerase II; and sensory organ precursor cell fate determination. Located in nucleus. Part of ISWI-type complex. Colocalizes with polytene chromosome. Is expressed in several structures, including adult head; antennal disc; epithelium; eye disc anterior to the morphogenetic furrow; and female germline cell. Orthologous to human CTBP1 (C-terminal binding protein 1) and CTBP2 (C-terminal binding protein 2). [provided by Alliance of Genome Resources, Oct 2024]

Genes similar to CtBP

NCBI Orthologs

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Species Gene Architecture aa