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ATG7 autophagy related 7 [ Gallus gallus (chicken) ]

Gene ID: 415961, updated on 10-Oct-2024

Summary

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Symbol
ATG7provided by CGNC
Full Name
autophagy related 7provided by CGNC
Primary source
CGNC:3663
See related
Ensembl:ENSGALG00010027247
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Also known as
APG7L
Orthologs
human mouse all
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Genomic context

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See ATG7 in Genome Data Viewer
Location:
chromosome: 12
Exon count:
21
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 12 NC_052543.1 (4568006..4666805)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 12 NC_052584.1 (4592178..4691066)

Chromosome 12 - NC_052543.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC107054455 Neighboring gene solute carrier family 6 member 1 Neighboring gene histamine receptor H1 Neighboring gene vestigial like family member 4 Neighboring gene uncharacterized LOC124417164 Neighboring gene TAM41 mitochondrial translocator assembly and maintenance homolog

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Atg7-Mediated Autophagy Is Involved in the Neural Crest Cell Generation in Chick Embryo. Wang G, et al. Mol Neurobiol, 2018 Apr. PMID 28509082
  2. ATG12 conjugation to ATG3 regulates mitochondrial homeostasis and cell death. Radoshevich L, et al. Cell, 2010 Aug 20. PMID 20723759, Free PMC Article
  3. Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis. Caldwell RB, et al. Genome Biol, 2005. PMID 15642098, Free PMC Article
  4. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables Atg12 activating enzyme activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables Atg8 activating enzyme activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in C-terminal protein lipidation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in autophagosome assembly IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in autophagy of mitochondrion IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cellular response to nitrogen starvation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in piecemeal microautophagy of the nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein modification by small protein conjugation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in phagophore assembly site IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
ubiquitin-like modifier-activating enzyme ATG7
Names
ATG12-activating enzyme E1 ATG7
ATG7 autophagy related 7 homolog
autophagy-related protein 7
ubiquitin-activating enzyme E1-like protein

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001030592.2 → NP_001025763.2  ubiquitin-like modifier-activating enzyme ATG7 isoform 1

    Status: VALIDATED

    Source sequence(s)
    JAENSK010000252
    UniProtKB/TrEMBL
    A0A8V1A851, A0A8V1AAR8
    Conserved Domains (1) summary
    TIGR01381
    Location:21 → 708
    E1_like_apg7; E1-like protein-activating enzyme Gsa7p/Apg7p

  2. NM_001396467.1 → NP_001383396.1  ubiquitin-like modifier-activating enzyme ATG7 isoform 1

    Status: VALIDATED

    Source sequence(s)
    JAENSK010000252
    UniProtKB/TrEMBL
    A0A8V1A851, A0A8V1AAR8
    Related
    ENSGALP00010040332.1, ENSGALT00010066066.1
    Conserved Domains (1) summary
    TIGR01381
    Location:21 → 708
    E1_like_apg7; E1-like protein-activating enzyme Gsa7p/Apg7p

  3. NM_001396468.1 → NP_001383397.1  ubiquitin-like modifier-activating enzyme ATG7 isoform 2

    Status: VALIDATED

    Source sequence(s)
    JAENSK010000252
    UniProtKB/TrEMBL
    A0A8V1A851
    Conserved Domains (1) summary
    TIGR01381
    Location:21 → 695
    E1_like_apg7; E1-like protein-activating enzyme Gsa7p/Apg7p

  4. NM_001396469.1 → NP_001383398.1  ubiquitin-like modifier-activating enzyme ATG7 isoform 3

    Status: VALIDATED

    Source sequence(s)
    JAENSK010000252
    UniProtKB/TrEMBL
    A0A8V1A851
    Conserved Domains (1) summary
    TIGR01381
    Location:21 → 643
    E1_like_apg7; E1-like protein-activating enzyme Gsa7p/Apg7p

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052543.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    4568006..4666805
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040646210.2 → XP_040502144.1  ubiquitin-like modifier-activating enzyme ATG7 isoform X1

    UniProtKB/TrEMBL
    A0A8V1A851, A0A8V1AAR8
    Related
    ENSGALP00010040330.1, ENSGALT00010066064.1
    Conserved Domains (1) summary
    TIGR01381
    Location:21 → 708
    E1_like_apg7; E1-like protein-activating enzyme Gsa7p/Apg7p

  2. XM_046899882.1 → XP_046755838.1  ubiquitin-like modifier-activating enzyme ATG7 isoform X2

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052584.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    4592178..4691066
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046926262.1 → XP_046782218.1  ubiquitin-like modifier-activating enzyme ATG7 isoform X1

    UniProtKB/Swiss-Prot
    Q5ZKY2

  2. XM_046926263.1 → XP_046782219.1  ubiquitin-like modifier-activating enzyme ATG7 isoform X2

Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q5ZKY2.1 GenPept UniProtKB/Swiss-Prot:Q5ZKY2

Gene LinkOut

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