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URAH 5-hydroxyisourate hydrolase [ Gallus gallus (chicken) ]

Gene ID: 415859, updated on 19-Sep-2023

Summary

Symbol
URAHprovided by CGNC
Full Name
5-hydroxyisourate hydrolaseprovided by CGNC
Primary source
CGNC:50101
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
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Genomic context

See URAH in Genome Data Viewer
Location:
chromosome: 11
Exon count:
4
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 11 NC_052542.1 (18508353..18509994, complement)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 11 NC_052583.1 (18856342..18857983, complement)

Chromosome 11 - NC_052542.1Genomic Context describing neighboring genes Neighboring gene dysbindin (dystrobrevin binding protein 1) domain containing 1 Neighboring gene growth arrest specific 8 Neighboring gene cadherin 3 Neighboring gene cadherin 1

Genomic regions, transcripts, and products

General protein information

Preferred Names
5-hydroxyisourate hydrolase
NP_001294879.2
XP_004944388.2
XP_025009963.2
XP_040563045.1
XP_046755471.1
XP_046755472.1
XP_046781594.1
XP_046781595.1
XP_046781596.1
XP_046781597.1
XP_046781598.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001307950.2NP_001294879.2  5-hydroxyisourate hydrolase

    Status: VALIDATED

    Source sequence(s)
    JAENSK010000248
    Conserved Domains (1) summary
    cd05822
    Location:15127
    TLP_HIUase; HIUase (5-hydroxyisourate hydrolase) catalyzes the second step in a three-step ureide pathway in which 5-hydroxyisourate (HIU), a product of the uricase (urate oxidase) reaction, is hydrolyzed to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU). ...

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052542.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    18508353..18509994 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040707111.2XP_040563045.1  5-hydroxyisourate hydrolase isoform X5

    Conserved Domains (1) summary
    cd05822
    Location:12124
    TLP_HIUase; HIUase (5-hydroxyisourate hydrolase) catalyzes the second step in a three-step ureide pathway in which 5-hydroxyisourate (HIU), a product of the uricase (urate oxidase) reaction, is hydrolyzed to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU). ...
  2. XM_046899516.1XP_046755472.1  5-hydroxyisourate hydrolase isoform X4

  3. XM_046899515.1XP_046755471.1  5-hydroxyisourate hydrolase isoform X3

  4. XM_004944331.5XP_004944388.2  5-hydroxyisourate hydrolase isoform X2

    Conserved Domains (1) summary
    cd05822
    Location:42154
    TLP_HIUase; HIUase (5-hydroxyisourate hydrolase) catalyzes the second step in a three-step ureide pathway in which 5-hydroxyisourate (HIU), a product of the uricase (urate oxidase) reaction, is hydrolyzed to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU). ...
  5. XM_025154195.3XP_025009963.2  5-hydroxyisourate hydrolase isoform X1

    Conserved Domains (1) summary
    cd05822
    Location:42163
    TLP_HIUase; HIUase (5-hydroxyisourate hydrolase) catalyzes the second step in a three-step ureide pathway in which 5-hydroxyisourate (HIU), a product of the uricase (urate oxidase) reaction, is hydrolyzed to 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU). ...

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052583.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    18856342..18857983 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046925642.1XP_046781598.1  5-hydroxyisourate hydrolase isoform X5

  2. XM_046925641.1XP_046781597.1  5-hydroxyisourate hydrolase isoform X4

  3. XM_046925640.1XP_046781596.1  5-hydroxyisourate hydrolase isoform X3

  4. XM_046925639.1XP_046781595.1  5-hydroxyisourate hydrolase isoform X2

  5. XM_046925638.1XP_046781594.1  5-hydroxyisourate hydrolase isoform X1