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CBFA2T3 CBFA2/RUNX1 translocation partner 3 [ Gallus gallus (chicken) ]

Gene ID: 415846, updated on 10-Oct-2024

Summary

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Symbol
CBFA2T3provided by CGNC
Full Name
CBFA2/RUNX1 translocation partner 3provided by CGNC
Primary source
CGNC:4681
See related
Ensembl:ENSGALG00010007930
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Also known as
MTG16a; MTG16b
Orthologs
human mouse all
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Genomic context

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See CBFA2T3 in Genome Data Viewer
Location:
chromosome: 11
Exon count:
14
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 11 NC_052542.1 (18169888..18191832, complement)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 11 NC_052583.1 (18517548..18539606, complement)

Chromosome 11 - NC_052542.1Genomic Context describing neighboring genes Neighboring gene trafficking protein particle complex 2 like Neighboring gene poly(A) binding protein nuclear 1 like, cytoplasmic Neighboring gene acyl-CoA synthetase family member 3 Neighboring gene uncharacterized LOC124417138 Neighboring gene cadherin 15

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The expression and function of MTG/ETO family proteins during neurogenesis. Koyano-Nakagawa N, et al. Dev Biol, 2005 Feb 1. PMID 15649458
  2. Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis. Caldwell RB, et al. Genome Biol, 2005. PMID 15642098, Free PMC Article
  3. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
  4. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  5. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables transcription corepressor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
protein CBFA2T3
Names
core-binding factor, runt domain, alpha subunit 2; translocated to, 3
myeloid translocation gene-related protein 2

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001030580.2 → NP_001025751.2  protein CBFA2T3

    Status: PROVISIONAL

    Source sequence(s)
    JAENSK010000248
    UniProtKB/Swiss-Prot
    Q5F3B1, Q5IJ74, Q5IJ75
    UniProtKB/TrEMBL
    A0A8V0Y2X1
    Related
    ENSGALP00010010476.1, ENSGALT00010018927.1
    Conserved Domains (3) summary
    smart00549
    Location:114 → 204
    TAFH; TAF homology
    COG2811
    Location:429 → 495
    NtpH; Archaeal/vacuolar-type H+-ATPase subunit H [Energy production and conversion]
    pfam08788
    Location:325 → 391
    NHR2; NHR2 domain like

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052542.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    18169888..18191832 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_025154190.3 → XP_025009958.2  protein CBFA2T3 isoform X2

    UniProtKB/Swiss-Prot
    Q5F3B1, Q5IJ74, Q5IJ75
    Conserved Domains (3) summary
    PTZ00121
    Location:319 → 510
    PTZ00121; MAEBL; Provisional
    smart00549
    Location:140 → 230
    TAFH; TAF homology
    pfam08788
    Location:351 → 417
    NHR2; NHR2 domain like

  2. XM_025154189.3 → XP_025009957.2  protein CBFA2T3 isoform X1

    UniProtKB/Swiss-Prot
    Q5F3B1, Q5IJ74, Q5IJ75
    UniProtKB/TrEMBL
    A0A8V0XZH1
    Related
    ENSGALP00010010473.1, ENSGALT00010018923.1
    Conserved Domains (3) summary
    smart00549
    Location:140 → 230
    TAFH; TAF homology
    COG2811
    Location:455 → 521
    NtpH; Archaeal/vacuolar-type H+-ATPase subunit H [Energy production and conversion]
    pfam08788
    Location:351 → 417
    NHR2; NHR2 domain like

  3. XM_025154193.3 → XP_025009961.2  protein CBFA2T3 isoform X4

    UniProtKB/Swiss-Prot
    Q5F3B1, Q5IJ74, Q5IJ75
    UniProtKB/TrEMBL
    A0A8V0Y2W1
    Related
    ENSGALP00010010466.1, ENSGALT00010018916.1
    Conserved Domains (4) summary
    COG2811
    Location:402 → 468
    NtpH; Archaeal/vacuolar-type H+-ATPase subunit H [Energy production and conversion]
    pfam08788
    Location:298 → 364
    NHR2; NHR2 domain like
    pfam01753
    Location:474 → 510
    zf-MYND; MYND finger
    pfam07531
    Location:87 → 175
    TAFH; NHR1 homology to TAF

  4. XM_025154191.3 → XP_025009959.2  protein CBFA2T3 isoform X3

    UniProtKB/Swiss-Prot
    Q5F3B1, Q5IJ74, Q5IJ75
    UniProtKB/TrEMBL
    A0A8V0Y2V5
    Related
    ENSGALP00010010461.1, ENSGALT00010018911.1
    Conserved Domains (4) summary
    COG2811
    Location:428 → 494
    NtpH; Archaeal/vacuolar-type H+-ATPase subunit H [Energy production and conversion]
    pfam08788
    Location:324 → 390
    NHR2; NHR2 domain like
    pfam01753
    Location:500 → 536
    zf-MYND; MYND finger
    pfam07531
    Location:113 → 201
    TAFH; NHR1 homology to TAF

  5. XM_025154192.3 → XP_025009960.2  protein CBFA2T3 isoform X3

    UniProtKB/Swiss-Prot
    Q5F3B1, Q5IJ74, Q5IJ75
    UniProtKB/TrEMBL
    A0A8V0Y2V5
    Conserved Domains (4) summary
    COG2811
    Location:428 → 494
    NtpH; Archaeal/vacuolar-type H+-ATPase subunit H [Energy production and conversion]
    pfam08788
    Location:324 → 390
    NHR2; NHR2 domain like
    pfam01753
    Location:500 → 536
    zf-MYND; MYND finger
    pfam07531
    Location:113 → 201
    TAFH; NHR1 homology to TAF

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052583.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    18517548..18539606 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046925607.1 → XP_046781563.1  protein CBFA2T3 isoform X2

  2. XM_046925606.1 → XP_046781562.1  protein CBFA2T3 isoform X1

  3. XM_046925609.1 → XP_046781565.1  protein CBFA2T3 isoform X4

    UniProtKB/TrEMBL
    A0A8V0Y2W1

  4. XM_046925608.1 → XP_046781564.1  protein CBFA2T3 isoform X3

    UniProtKB/TrEMBL
    A0A8V0Y2V5

  5. XM_046925611.1 → XP_046781567.1  protein CBFA2T3 isoform X3

    UniProtKB/TrEMBL
    A0A8V0Y2V5
Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q5F3B1.1 GenPept UniProtKB/Swiss-Prot:Q5F3B1

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