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Ugt37A3 UDP-glycosyltransferase family 37 member A3 [ Drosophila melanogaster (fruit fly) ]

Gene ID: 41574, updated on 18-Sep-2024

Summary

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Official Symbol
Ugt37A3provided by FlyBase
Official Full Name
UDP-glycosyltransferase family 37 member A3provided by FlyBase
Primary source
FLYBASE:FBgn0038083
Locus tag
Dmel_CG5999
See related
AllianceGenome:FB:FBgn0038083
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Drosophila melanogaster
Lineage
Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
Also known as
CG5999; Dmel\CG5999; UGT37A3
Summary
Predicted to enable UDP-glycosyltransferase activity. Predicted to be active in intracellular membrane-bounded organelle. Is expressed in adult head. Human ortholog(s) of this gene implicated in several diseases, including alcoholic pancreatitis; bilirubin metabolic disorder (multiple); cholecystolithiasis; cholelithiasis; and female reproductive organ cancer (multiple). Orthologous to several human genes including UGT1A1 (UDP glucuronosyltransferase family 1 member A1); UGT1A10 (UDP glucuronosyltransferase family 1 member A10); and UGT1A3 (UDP glucuronosyltransferase family 1 member A3). [provided by Alliance of Genome Resources, Apr 2022]
Orthologs
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Genomic context

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See Ugt37A3 in Genome Data Viewer
Location:
87C8-87C8; 3-52 cM
Exon count:
2
Annotation release Status Assembly Chr Location
Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3R NT_033777.3 (12741958..12743680, complement)
Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3R NT_033777.2 (8567680..8569402, complement)

Chromosome 3R - NT_033777.3Genomic Context describing neighboring genes Neighboring gene long non-coding RNA:CR44231 Neighboring gene long non-coding RNA:CR46238 Neighboring gene UDP-glycosyltransferase family 37 member A2 Neighboring gene beaten path Vc Neighboring gene long non-coding RNA:CR44233

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Effects of lithium chloride on the gene expression profiles in Drosophila heads. Kasuya J, et al. Neurosci Res, 2009 Aug. PMID 19410610, Free PMC Article
  2. Genome-wide transcription analysis of clinal genetic variation in Drosophila. Chen Y, et al. PLoS One, 2012. PMID 22514645, Free PMC Article
  3. The requirement of IRE1 and XBP1 in resolving physiological stress during Drosophila development. Huang HW, et al. J Cell Sci, 2017 Sep 15. PMID 28775151, Free PMC Article
  4. The UDP-Glycosyltransferase Family in Drosophila melanogaster: Nomenclature Update, Gene Expression and Phylogenetic Analysis. Ahn SJ, et al. Front Physiol, 2021. PMID 33815151, Free PMC Article
  5. Defensive repertoire of Drosophila larvae in response to toxic fungi. Trienens M, et al. Mol Ecol, 2017 Oct. PMID 28746736

See all (45) citations in PubMed

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by FlyBase

Function Evidence Code Pubs
enables UDP-glycosyltransferase activity IBA
Inferred from Biological aspect of Ancestor
more info
  
enables UDP-glycosyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables UDP-glycosyltransferase activity ISM
Inferred from Sequence Model
more info
 PubMed 
Process Evidence Code Pubs
involved_in glycosylation ISM
Inferred from Sequence Model
more info
 PubMed 
Component Evidence Code Pubs
is_active_in endoplasmic reticulum membrane ISM
Inferred from Sequence Model
more info
 PubMed 

General protein information

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Preferred Names
UDP-glycosyltransferase family 37 member A3
Names
CG5999-PB
Ugt37A3-PB

NCBI Reference Sequences (RefSeq)

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Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NT_033777.3 Reference assembly

    Range
    12741958..12743680 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_141972.2 → NP_650229.2  UDP-glycosyltransferase family 37 member A3 [Drosophila melanogaster]

    See identical proteins and their annotated locations for NP_650229.2

    Status: REVIEWED

    UniProtKB/TrEMBL
    C0P8M3, Q9VG29
    Conserved Domains (2) summary
    PHA03392
    Location:1 → 490
    egt; ecdysteroid UDP-glucosyltransferase; Provisional
    pfam00201
    Location:37 → 526
    UDPGT; UDP-glucoronosyl and UDP-glucosyl transferase
Nucleotide Protein
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q9VG29 Q9VG29

Gene LinkOut

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