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WDR59 WD repeat domain 59 [ Gallus gallus (chicken) ]

Gene ID: 415688, updated on 10-Oct-2024

Summary

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Symbol
WDR59provided by CGNC
Full Name
WD repeat domain 59provided by CGNC
Primary source
CGNC:2018
See related
Ensembl:ENSGALG00010023335
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Orthologs
human mouse all
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Genomic context

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See WDR59 in Genome Data Viewer
Location:
chromosome: 11
Exon count:
27
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 11 NC_052542.1 (1922165..1970763, complement)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 11 NC_052583.1 (2094572..2143168, complement)

Chromosome 11 - NC_052542.1Genomic Context describing neighboring genes Neighboring gene mixed lineage kinase domain like pseudokinase Neighboring gene fatty acid 2-hydroxylase Neighboring gene microRNA 1643 Neighboring gene zinc and ring finger 1 Neighboring gene lactate dehydrogenase D Neighboring gene chymotrypsinogen B1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Full-length cDNAs from chicken bursal lymphocytes to facilitate gene function analysis. Caldwell RB, et al. Genome Biol, 2005. PMID 15642098, Free PMC Article
  2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article
  3. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article

GeneRIFs: Gene References Into Functions

Pathways from PubChem

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General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
GATOR2 complex protein WDR59; GATOR complex protein WDR59
Names
WD repeat-containing protein 59

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001012776.2 → NP_001012794.1  GATOR2 complex protein WDR59

    See identical proteins and their annotated locations for NP_001012794.1

    Status: PROVISIONAL

    Source sequence(s)
    JAENSK010000247
    UniProtKB/Swiss-Prot
    Q5ZLG9
    UniProtKB/TrEMBL
    A0A8V0ZUT0
    Related
    ENSGALP00010034599.1, ENSGALT00010056900.1
    Conserved Domains (5) summary
    COG2319
    Location:34 → 340
    WD40; WD40 repeat [General function prediction only]
    sd00039
    Location:62 → 103
    7WD40; WD40 repeat [structural motif]
    cl02567
    Location:101 → 319
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    cl02687
    Location:394 → 493
    RWD; RWD domain
    cl24077
    Location:923 → 971
    Zn_ribbon_17; Zinc-ribbon, C4HC2 type

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052542.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    1922165..1970763 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015279138.4 → XP_015134624.1  GATOR complex protein WDR59 isoform X2

    UniProtKB/TrEMBL
    A0A8V0ZMI1, A0A8V0ZUT0
    Related
    ENSGALP00010034595.1, ENSGALT00010056888.1
    Conserved Domains (5) summary
    COG2319
    Location:34 → 340
    WD40; WD40 repeat [General function prediction only]
    sd00039
    Location:62 → 103
    7WD40; WD40 repeat [structural motif]
    cl02567
    Location:101 → 319
    WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
    cl02687
    Location:394 → 493
    RWD; RWD domain
    cl24077
    Location:942 → 990
    Zn_ribbon_17; Zinc-ribbon, C4HC2 type

  2. XM_025154156.3 → XP_025009924.1  GATOR complex protein WDR59 isoform X3

    UniProtKB/TrEMBL
    A0A8V0ZSR1, A0A8V0ZUT0
    Related
    ENSGALP00010034592.1, ENSGALT00010056884.1
    Conserved Domains (4) summary
    COG2319
    Location:36 → 342
    WD40; WD40 repeat [General function prediction only]
    sd00039
    Location:64 → 105
    7WD40; WD40 repeat [structural motif]
    cd16692
    Location:923 → 969
    mRING-H2-C3H3C2_WDR59; Modified RING finger, H2 subclass (C3H3C2-type), found in WD repeat-containing protein 59 (WDR59) and similar proteins
    cl02687
    Location:396 → 495
    RWD; RWD domain

  3. XM_040707043.2 → XP_040562977.1  GATOR complex protein WDR59 isoform X1

    UniProtKB/TrEMBL
    A0A8V0ZUT0
    Conserved Domains (4) summary
    COG2319
    Location:36 → 342
    WD40; WD40 repeat [General function prediction only]
    sd00039
    Location:64 → 105
    7WD40; WD40 repeat [structural motif]
    cd16692
    Location:942 → 988
    mRING-H2-C3H3C2_WDR59; Modified RING finger, H2 subclass (C3H3C2-type), found in WD repeat-containing protein 59 (WDR59) and similar proteins
    cl02687
    Location:396 → 495
    RWD; RWD domain

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_052583.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    2094572..2143168 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046925439.1 → XP_046781395.1  GATOR complex protein WDR59 isoform X2

    UniProtKB/TrEMBL
    A0A8V0ZMI1

  2. XM_046925440.1 → XP_046781396.1  GATOR complex protein WDR59 isoform X3

    UniProtKB/TrEMBL
    A0A8V0ZSR1

  3. XM_046925438.1 → XP_046781394.1  GATOR complex protein WDR59 isoform X1

Nucleotide Protein Strain
Heading Accession and Version
Protein Accession Links
GenPept Link UniProtKB Link
Q5ZLG9.1 GenPept UniProtKB/Swiss-Prot:Q5ZLG9

Gene LinkOut

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