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rela - v-rel avian reticuloendotheliosis viral oncogene homolog A

Enables DNA-binding transcription factor activity, RNA polymerase II-specific. Acts upstream of or within several processes, including defense response to virus; positive regulation of DNA-templated transcription; and regulation of apoptotic process. Located in nucleus. Is expressed in intestine; kidney; liver; male organism; and posterior intestine. Human ortholog(s) of this gene implicated in ductal carcinoma in situ; lung non-small cell carcinoma; lymphoma; and renal cell carcinoma. Orthologous to human RELA (RELA proto-oncogene, NF-kB subunit). [provided by Alliance of Genome Resources, Oct 2024]

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Species Gene Architecture aa