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Sfta2 surfactant associated 2 [ Rattus norvegicus (Norway rat) ]

Gene ID: 415052, updated on 28-Oct-2024

Summary

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Official Symbol
Sfta2provided by RGD
Official Full Name
surfactant associated 2provided by RGD
Primary source
RGD:1303180
See related
EnsemblRapid:ENSRNOG00000048987 AllianceGenome:RGD:1303180
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
E030032D13Rik
Summary
Orthologous to human SFTA2 (surfactant associated 2). [provided by Alliance of Genome Resources, Oct 2024]
Expression
Restricted expression toward (RPKM 140.9) See more
Orthologs
human mouse all
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Genomic context

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See Sfta2 in Genome Data Viewer
Location:
20p12
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 20 NC_086038.1 (3098313..3099038, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 20 NC_051355.1 (3093569..3094299, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 20 NC_005119.4 (3604918..3605643, complement)

Chromosome 20 - NC_086038.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134483850 Neighboring gene general transcription factor 2H subunit 4 Neighboring gene valyl-tRNA synthetase 2, mitochondrial Neighboring gene mucin like 3 Neighboring gene CB741658 gene

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Expression

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  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

  1. Localization, Occurrence, and CSF Changes of SP-G, a New Surface Active Protein with Assumable Immunoregulatory Functions in the CNS. Krause M, et al. Mol Neurobiol, 2019 Apr. PMID 30032421
  2. The genomic sequence and comparative analysis of the rat major histocompatibility complex. Hurt P, et al. Genome Res, 2004 Apr. PMID 15060004, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?
  1. SP-G is a potential new cerebrospinal fluid (CSF) biomarker, possibly not only reflecting aspects of CNS innate immune responses, but also rheo-dynamically relevant changes of CSF composition.
    Title: Localization, Occurrence, and CSF Changes of SP-G, a New Surface Active Protein with Assumable Immunoregulatory Functions in the CNS.
Submit: New GeneRIF Correction

General gene information

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Markers

Homology

General protein information

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Preferred Names
surfactant-associated protein 2
Names
surfactant associated protein G

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001166020.1 → NP_001159492.1  surfactant-associated protein 2 precursor

    See identical proteins and their annotated locations for NP_001159492.1

    Status: VALIDATED

    Source sequence(s)
    BX883047
    UniProtKB/TrEMBL
    A6KTA6
    Related
    ENSRNOP00000066911.3, ENSRNOT00000074460.4
    Conserved Domains (1) summary
    pfam15210
    Location:19 → 78
    SFTA2; Surfactant-associated protein 2

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086038.1 Reference GRCr8

    Range
    3098313..3099038 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NR_002149.1: Suppressed sequence

    Description
    NR_002149.1: This RefSeq was permanently suppressed because it is now thought that this gene does encode a protein.
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.