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ST8SIA5 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5 [ Gallus gallus (chicken) ]

Gene ID: 414797, updated on 10-Oct-2024

Summary

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Official Symbol
ST8SIA5provided by CGNC
Official Full Name
ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 5provided by CGNC
Primary source
CGNC:1273
See related
Ensembl:ENSGALG00010009858
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Gallus gallus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
Also known as
SIAT8E
Orthologs
human mouse all
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Genomic context

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See ST8SIA5 in Genome Data Viewer
Location:
chromosome: Z
Exon count:
15
Annotation release Status Assembly Chr Location
106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) Z NC_052572.1 (2153909..2213607)
106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) Z NC_059536.1 (2153909..2213607)

Chromosome Z - NC_052572.1Genomic Context describing neighboring genes Neighboring gene katanin catalytic subunit A1 like 2 Neighboring gene haloacid dehalogenase like hydrolase domain containing 2 Neighboring gene uncharacterized LOC107051906 Neighboring gene protein inhibitor of activated STAT 2 Neighboring gene lipoxygenase homology domains 1 Neighboring gene ring finger protein 165

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. The animal sialyltransferases and sialyltransferase-related genes: a phylogenetic approach. Harduin-Lepers A, et al. Glycobiology, 2005 Aug. PMID 15843597
  2. Manual GO annotation of predictive protein signatures: the InterPro approach to GO curation. Burge S, et al. Database (Oxford), 2012. PMID 22301074, Free PMC Article
  3. TreeGrafter: phylogenetic tree-based annotation of proteins with Gene Ontology terms and other annotations. Tang H, et al. Bioinformatics, 2019 Feb 1. PMID 30032202, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in N-glycan processing IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in oligosaccharide metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein glycosylation IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
alpha-2,8-sialyltransferase 8E
Names
alpha-2,8-syalyltransferase ST8Sia-V
NP_001001747.2
NP_001383392.1
XP_004949086.1
XP_004949089.1
XP_015132898.1
XP_015132901.1
XP_040511410.1
XP_046761238.1
XP_046761239.1
XP_046761240.1
XP_046761241.1
XP_046790876.1
XP_046790877.1
XP_046790878.1
XP_046790879.1
XP_046790880.1
XP_046790881.1
XP_046790882.1
XP_046790883.1
XP_046790884.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001001747.3 → NP_001001747.2  alpha-2,8-sialyltransferase 8E isoform 2

    Status: VALIDATED

    Source sequence(s)
    JAENSK010000086
    UniProtKB/TrEMBL
    A0A3Q2TZK0, Q6ZX98
    Related
    ENSGALP00010013564.1, ENSGALT00010023546.1
    Conserved Domains (1) summary
    pfam00777
    Location:117 → 370
    Glyco_transf_29; Glycosyltransferase family 29 (sialyltransferase)

  2. NM_001396463.1 → NP_001383392.1  alpha-2,8-sialyltransferase 8E isoform 1

    Status: VALIDATED

    Source sequence(s)
    JAENSK010000086
    UniProtKB/TrEMBL
    A0A1D5PGU4, A0A1D5PIR8, Q6ZX98
    Conserved Domains (1) summary
    pfam00777
    Location:153 → 406
    Glyco_transf_29; Glycosyltransferase family 29 (sialyltransferase)

RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

Genomic

  1. NC_052572.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Range
    2153909..2213607
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046905282.1 → XP_046761238.1  alpha-2,8-sialyltransferase 8E isoform X1

    UniProtKB/TrEMBL
    A0A1D5PGU4, A0A1D5PIR8

  2. XM_004949029.5 → XP_004949086.1  alpha-2,8-sialyltransferase 8E isoform X1

    See identical proteins and their annotated locations for XP_004949086.1

    UniProtKB/TrEMBL
    A0A1D5PGU4, A0A1D5PIR8, Q6ZX98
    Conserved Domains (1) summary
    pfam00777
    Location:153 → 406
    Glyco_transf_29; Glycosyltransferase family 29 (sialyltransferase)

  3. XM_046905283.1 → XP_046761239.1  alpha-2,8-sialyltransferase 8E isoform X1

    UniProtKB/TrEMBL
    A0A1D5PGU4, A0A1D5PIR8

  4. XM_046905285.1 → XP_046761241.1  alpha-2,8-sialyltransferase 8E isoform X1

    UniProtKB/TrEMBL
    A0A1D5PGU4, A0A1D5PIR8
    Related
    ENSGALP00010013563.1, ENSGALT00010023541.1

  5. XM_015277412.4 → XP_015132898.1  alpha-2,8-sialyltransferase 8E isoform X1

    UniProtKB/TrEMBL
    A0A1D5PGU4, A0A1D5PIR8, Q6ZX98
    Conserved Domains (1) summary
    pfam00777
    Location:153 → 406
    Glyco_transf_29; Glycosyltransferase family 29 (sialyltransferase)

  6. XM_046905284.1 → XP_046761240.1  alpha-2,8-sialyltransferase 8E isoform X1

    UniProtKB/TrEMBL
    A0A1D5PGU4, A0A1D5PIR8

  7. XM_015277415.4 → XP_015132901.1  alpha-2,8-sialyltransferase 8E isoform X2

    UniProtKB/TrEMBL
    A0A3Q2TZK0, Q6ZX98
    Conserved Domains (1) summary
    pfam00777
    Location:117 → 370
    Glyco_transf_29; Glycosyltransferase family 29 (sialyltransferase)

  8. XM_004949032.5 → XP_004949089.1  alpha-2,8-sialyltransferase 8E isoform X1

    See identical proteins and their annotated locations for XP_004949089.1

    UniProtKB/TrEMBL
    A0A1D5PGU4, A0A1D5PIR8, Q6ZX98
    Conserved Domains (1) summary
    pfam00777
    Location:153 → 406
    Glyco_transf_29; Glycosyltransferase family 29 (sialyltransferase)

  9. XM_040655476.2 → XP_040511410.1  alpha-2,8-sialyltransferase 8E isoform X2

    UniProtKB/TrEMBL
    A0A3Q2TZK0, Q6ZX98
    Conserved Domains (1) summary
    pfam00777
    Location:117 → 370
    Glyco_transf_29; Glycosyltransferase family 29 (sialyltransferase)

Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

Genomic

  1. NC_059536.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Range
    2153909..2213607
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_046934923.1 → XP_046790879.1  alpha-2,8-sialyltransferase 8E isoform X1

    UniProtKB/TrEMBL
    A0A1D5PGU4, A0A1D5PIR8

  2. XM_046934921.1 → XP_046790877.1  alpha-2,8-sialyltransferase 8E isoform X1

    UniProtKB/TrEMBL
    A0A1D5PGU4, A0A1D5PIR8

  3. XM_046934924.1 → XP_046790880.1  alpha-2,8-sialyltransferase 8E isoform X1

    UniProtKB/TrEMBL
    A0A1D5PGU4, A0A1D5PIR8

  4. XM_046934926.1 → XP_046790882.1  alpha-2,8-sialyltransferase 8E isoform X1

    UniProtKB/TrEMBL
    A0A1D5PGU4, A0A1D5PIR8

  5. XM_046934922.1 → XP_046790878.1  alpha-2,8-sialyltransferase 8E isoform X1

    UniProtKB/TrEMBL
    A0A1D5PGU4, A0A1D5PIR8

  6. XM_046934925.1 → XP_046790881.1  alpha-2,8-sialyltransferase 8E isoform X1

    UniProtKB/TrEMBL
    A0A1D5PGU4, A0A1D5PIR8

  7. XM_046934927.1 → XP_046790883.1  alpha-2,8-sialyltransferase 8E isoform X2

    UniProtKB/TrEMBL
    A0A3Q2TZK0

  8. XM_046934920.1 → XP_046790876.1  alpha-2,8-sialyltransferase 8E isoform X1

    UniProtKB/TrEMBL
    A0A1D5PGU4, A0A1D5PIR8

  9. XM_046934928.1 → XP_046790884.1  alpha-2,8-sialyltransferase 8E isoform X2

    UniProtKB/TrEMBL
    A0A3Q2TZK0
Nucleotide Protein
Heading Accession and Version

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