RT1-CE11 RT1 class I, locus CE11 [Rattus norvegicus (Norway rat)] - Gene

Summary

Symbol: RT1-CE11provided by RGD
Full Name: RT1 class I, locus CE11provided by RGD
Primary source: RGD:1359483
See related: AllianceGenome:RGD:1359483
Gene type: protein coding
RefSeq status: VALIDATED
Organism: Rattus norvegicus
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as: RT1-CE10
Summary: Predicted to be located in lumenal side of endoplasmic reticulum membrane and phagocytic vesicle membrane. Predicted to be part of MHC class I protein complex. [provided by Alliance of Genome Resources, Nov 2024]
NEW: Try the new Gene table
Try the new Transcript table

Genomic context

Location:: 20p12

Exon count:: 16

Annotation release	Status	Assembly	Chr	Location
RS_2024_02	current	GRCr8 (GCF_036323735.1)	20	NC_086038.1 (3355422..3385063, complement)
RS_2023_06	previous assembly	mRatBN7.2 (GCF_015227675.2)	20	NC_051355.1 (3355393..3358520, complement)

Chromosome 20 - NC_086038.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

Go to the top of the page Help

Go to reference sequence details

Genomic Sequence:

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the page Help

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Submit: New GeneRIF Correction

General gene information

Go to the top of the page Help

Gene Ontology Provided by RGD

Function	Evidence Code	Pubs
enables peptide antigen binding	IBA Inferred from Biological aspect of Ancestor more info
enables signaling receptor binding	IBA Inferred from Biological aspect of Ancestor more info

Process	Evidence Code	Pubs
involved_in antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent	IBA Inferred from Biological aspect of Ancestor more info
involved_in antigen processing and presentation of endogenous peptide antigen via MHC class Ib	IBA Inferred from Biological aspect of Ancestor more info
involved_in immune response	IBA Inferred from Biological aspect of Ancestor more info
involved_in positive regulation of T cell mediated cytotoxicity	IBA Inferred from Biological aspect of Ancestor more info

Component	Evidence Code	Pubs
part_of MHC class I protein complex	IEA Inferred from Electronic Annotation more info
is_active_in external side of plasma membrane	IBA Inferred from Biological aspect of Ancestor more info
is_active_in extracellular space	IBA Inferred from Biological aspect of Ancestor more info
located_in lumenal side of endoplasmic reticulum membrane	IEA Inferred from Electronic Annotation more info
located_in phagocytic vesicle membrane	IEA Inferred from Electronic Annotation more info

General protein information

Go to the top of the page Help

Preferred Names: RT1 class I, locus CE11

Names: H-2 class I histocompatibility antigen, alpha chain-like; RT1 class I, CE10; RT1 class I, CE11

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001008834.2 → NP_001008834.1 RT1 class I, locus CE11 precursor

See identical proteins and their annotated locations for NP_001008834.1

Status: VALIDATED

Source sequence(s)

JAXUCZ010000020

UniProtKB/TrEMBL

Q6MG33

Conserved Domains (3) summary

cd07698
Location:207 → 299

IgC_MHC_I_alpha3; Class I major histocompatibility complex (MHC) alpha chain immunoglobulin domain

pfam00129
Location:25 → 203

MHC_I; Class I Histocompatibility antigen, domains alpha 1 and 2

pfam06623
Location:340 → 366

MHC_I_C; MHC_I C-terminus

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

NC_086038.1 Reference GRCr8

Range

3355422..3385063 complement

Download

GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

XM_063279413.1 → XP_063135483.1 RT1 class I, locus CE11 isoform X5
XM_063279410.1 → XP_063135480.1 RT1 class I, locus CE11 isoform X2
XM_063279411.1 → XP_063135481.1 RT1 class I, locus CE11 isoform X3
XM_063279409.1 → XP_063135479.1 RT1 class I, locus CE11 isoform X1
XM_063279415.1 → XP_063135485.1 RT1 class I, locus CE11 isoform X7

UniProtKB/TrEMBL

A0A2P1NRY1
XM_063279412.1 → XP_063135482.1 RT1 class I, locus CE11 isoform X4
XM_063279416.1 → XP_063135486.1 RT1 class I, locus CE11 isoform X8
XM_063279414.1 → XP_063135484.1 RT1 class I, locus CE11 isoform X6