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mgat2.L mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase L homeolog [ Xenopus laevis (African clawed frog) ]

Gene ID: 414590, updated on 4-Nov-2024

Summary

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Official Symbol
mgat2.L
Official Full Name
mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase L homeolog
Primary source
Xenbase:XB-GENE-978795
Locus tag
XELAEV_18039632mg
See related
EnsemblRapid:ENSXLAG00005018813 AllianceGenome:Xenbase:XB-GENE-978795
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Xenopus laevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as
mgat2
Summary
Predicted to enable alpha-1,6-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity and metal ion binding activity. Predicted to act upstream of or within oligosaccharide biosynthetic process and protein N-linked glycosylation. Predicted to be located in Golgi membrane and Golgi stack. Human ortholog(s) of this gene implicated in congenital disorder of glycosylation type IIa. Orthologous to human MGAT2 (alpha-1,6-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase). [provided by Alliance of Genome Resources, Nov 2024]
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Genomic context

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See mgat2.L in Genome Data Viewer
Location:
chromosome: 8L
Exon count:
2
Annotation release Status Assembly Chr Location
101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 8L NC_054385.1 (84113279..84118248, complement)
100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 8L NC_030738.1 (69425975..69430944, complement)

Chromosome 8L - NC_054385.1Genomic Context describing neighboring genes Neighboring gene kelch domain containing 1 L homeolog Neighboring gene polymerase (DNA directed), epsilon 2, accessory subunit L homeolog Neighboring gene dynein, axonemal, assembly factor 2 L homeolog Neighboring gene leucine rich repeat protein 1 L homeolog Neighboring gene 40S ribosomal protein S29

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Genetic and genomic tools for Xenopus research: The NIH Xenopus initiative. Klein SL, et al. Dev Dyn, 2002 Dec. PMID 12454917
  2. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, et al. Proc Natl Acad Sci U S A, 2002 Dec 24. PMID 12477932, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Clone Names

  • MGC83215

Gene Ontology Provided by Xenbase

Function Evidence Code Pubs
enables alpha-1,6-mannosylglycoprotein 2-beta-N-acetylglucosaminyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables glycosyltransferase activity IEA
Inferred from Electronic Annotation
more info
  
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
  
Process Evidence Code Pubs
acts_upstream_of_or_within oligosaccharide biosynthetic process IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within protein N-linked glycosylation IEA
Inferred from Electronic Annotation
more info
  
acts_upstream_of_or_within protein glycosylation IEA
Inferred from Electronic Annotation
more info
  
Component Evidence Code Pubs
located_in Golgi apparatus IEA
Inferred from Electronic Annotation
more info
  
located_in Golgi membrane IEA
Inferred from Electronic Annotation
more info
  
located_in Golgi stack IEA
Inferred from Electronic Annotation
more info
  
located_in membrane IEA
Inferred from Electronic Annotation
more info
  

General protein information

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Preferred Names
mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase L homeolog
NP_001084633.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001091164.1 → NP_001084633.1  mannosyl (alpha-1,6-)-glycoprotein beta-1,2-N-acetylglucosaminyltransferase L homeolog

    See identical proteins and their annotated locations for NP_001084633.1

    Status: PROVISIONAL

    Source sequence(s)
    BC068949
    UniProtKB/TrEMBL
    A0A974C876, Q6NTL2
    Related
    ENSXLAP00005055565.1, ENSXLAT00005056770.1
    Conserved Domains (1) summary
    pfam05060
    Location:79 → 425
    MGAT2; N-acetylglucosaminyltransferase II (MGAT2)

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

  1. NC_054385.1 Reference Xenopus_laevis_v10.1 Primary Assembly

    Range
    84113279..84118248 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
Nucleotide Protein Strain
Heading Accession and Version

Gene LinkOut

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