nosip.S nitric oxide synthase interacting protein S homeolog [Xenopus laevis (African clawed frog)] - Gene

Summary

Official Symbol: nosip.S
Official Full Name: nitric oxide synthase interacting protein S homeolog
Primary source: Xenbase:XB-GENE-945894
Locus tag: XELAEV_18037778mg
See related: EnsemblRapid:ENSXLAG00005011733
Gene type: protein coding
RefSeq status: PROVISIONAL
Organism: Xenopus laevis
Lineage: Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
Also known as: nosip
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Genomic context

Location:: chromosome: 7S

Exon count:: 10

Annotation release	Status	Assembly	Chr	Location
101	current	Xenopus_laevis_v10.1 (GCF_017654675.1)	7S	NC_054384.1 (96759646..96774772, complement)
100	previous assembly	Xenopus_laevis_v2 (GCF_001663975.1)	7S	NC_030737.1 (77619804..77634959, complement)

Chromosome 7S - NC_054384.1 Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:

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Bibliography

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GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Nosip is a crucial factor for the development of anterior neural tissue such as the eyes and neural crest cells.
Title: Nosip functions during vertebrate eye and cranial cartilage development.
Nosip is a novel factor critical for neural stem cell/progenitor self-renewal and neurogenesis during mouse and Xenopus development.
Title: Developmental neurogenesis in mouse and Xenopus is impaired in the absence of Nosip.

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General gene information

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Gene Ontology Provided by Xenbase

Function	Evidence Code	Pubs
enables transferase activity	IEA Inferred from Electronic Annotation more info
enables ubiquitin protein ligase activity	IEA Inferred from Electronic Annotation more info

Component	Evidence Code	Pubs
located_in cytoplasm	IEA Inferred from Electronic Annotation more info
located_in nucleus	IEA Inferred from Electronic Annotation more info

General protein information

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Preferred Names: nitric oxide synthase-interacting protein

Names: E3 ubiquitin-protein ligase NOSIP; RING-type E3 ubiquitin transferase NOSIP

NP_001084604.1

EC 2.3.2.27

XP_018082380.1

EC 2.3.2.27

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

NM_001091135.1 → NP_001084604.1 nitric oxide synthase-interacting protein

See identical proteins and their annotated locations for NP_001084604.1

Status: PROVISIONAL

Source sequence(s)

BC068614

UniProtKB/Swiss-Prot

Q6NUH3

Related

ENSXLAP00005034249.1, ENSXLAT00005035133.1

Conserved Domains (2) summary

pfam15906
Location:4 → 78

zf-NOSIP; Zinc-finger of nitric oxide synthase-interacting protein

cl17238
Location:218 → 271

RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...

RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Xenopus_laevis_v10.1 Primary Assembly

Genomic

NC_054384.1 Reference Xenopus_laevis_v10.1 Primary Assembly

Range

96759646..96774772 complement

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GenBank, FASTA, Sequence Viewer (Graphics)